PMID: 7540379Apr 21, 1995Paper

Gene expression and phosphorylation of mouse osteopontin

Annals of the New York Academy of Sciences
R A SaavedraC I Ljubetic

Abstract

Osteopontin is expressed in many different cell types and has been proposed to play several functions. Distinct forms of the protein have been detected. Various tissues and cell lines from mouse, however, exhibit two classes of transcripts with different 5'-untranslated ends but with an identical coding region (exons II through VII). These transcripts do not arise from the alternative splicing of coding exons. These results suggest that posttranslational modifications of osteopontin, such as phosphorylation, are a major mechanism to generate different forms of the protein. Mouse osteopontin was expressed in E. coli and used as a model to study its phosphorylation.

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Citations

Oct 29, 2011·Cell Biology International·Hong GaoKenneth S Ramos
Oct 6, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J SodekM D McKee

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