Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Nucleic Acids Research
Ron EdgarAlex E Lash

Abstract

The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-throughput gene expression and genomic hybridization experiments. GEO is not intended to replace in house gene expression databases that benefit from coherent data sets, and which are constructed to facilitate a particular analytic method, but rather complement these by acting as a tertiary, central data distribution hub. The three central data entities of GEO are platforms, samples and series, and were designed with gene expression and genomic hybridization experiments in mind. A platform is, essentially, a list of probes that define what set of molecules may be detected. A sample describes the set of molecules that are being probed and references a single platform used to generate its molecular abundance data. A series organizes samples into the meaningful data sets which make up an experiment. The GEO repository is publicly accessible through the World Wide Web at http://www.ncbi.nlm.nih.gov/geo.

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Jan 27, 2009·BMC Bioinformatics·Bart Hj van den BergShane C Burgess
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Jul 13, 2012·BMC Bioinformatics·John D EblenMichael A Langston
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Feb 25, 2005·BMC Bioinformatics·Tim LuStefan Schreiber
Mar 8, 2005·BMC Bioinformatics·Wen-Chieh ChangBor-Sen Chen
Jul 20, 2005·BMC Bioinformatics·Nikhil R GargeDavid B Allison
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