Gene expression profiles of fathead minnows exposed to surface waters above and below a sewage treatment plant in Minnesota.

Marine Environmental Research
Natalia Garcia-ReyeroNancy D Denslow

Abstract

Water treatment plants are often not effective in removing pharmaceuticals, personal care products or natural hormones from their effluents. To test the effects of these effluents on fish, we exposed male fathead minnows (Pimephales promelas) for 48h to effluents at two sites, one up-stream and the other down-stream from a water treatment plant. Gene expression profiling showed that significant changes occurred in the gonad of fish exposed below, compared to above the treatment plant and to laboratory control fish. Among the biological processes affected were the innate immune response, response to stress, control of homeostasis, control of transcription, metabolism, and cell communication. This work suggests that fish are impacted by exposures to the sewage treatment effluents and effects can be detected rapidly by gene expression profiling.

References

Dec 11, 1999·Environmental Health Perspectives·C G Daughton, T A Ternes
Jul 13, 2002·Archives of Environmental Contamination and Toxicology·D B HuggettD Schlenk

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Citations

Feb 15, 2016·Aquatic Toxicology·Vicki L MarlattChristopher J Martyniuk
Jan 16, 2016·Environmental Toxicology and Chemistry·Paulina A BahamondeChristopher J Martyniuk
Feb 28, 2014·Integrated Environmental Assessment and Management·Sharon E HookGraeme E Batley
Jun 28, 2008·Journal of Fish Biology·Natàlia Garcia-ReyeroNancy D Denslow
Apr 10, 2013·The Science of the Total Environment·Anna NavarroBenjamin Piña
Sep 26, 2013·The Science of the Total Environment·Matthias HasenbeinRichard E Connon
Jun 29, 2013·Marine Pollution Bulletin·Sarah J BourlatMatthias Obst
Oct 23, 2016·Fish & Shellfish Immunology·Mario Alberto Burgos-AcevesCaterina Faggio
Jul 29, 2011·Environmental Science & Technology·Doris E Vidal-DorschChris Vulpe

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