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Gene-Gene Interactions Detection Using a Two-stage Model

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology

Apr 15, 2015

Zhanyong WangEleazar Eskin

Abstract

Genome-wide association studies (GWAS) have discovered numerous loci involved in genetic traits. Virtually all studies have reported associations between individual single nucleotide polymorphisms (SNPs) and traits. However, it is likely that complex traits are influenced by interaction...read more

Mentioned in this Paper

Biological Markers
Genome-Wide Association Study
Study
Laboratory Procedures
Joints
Computer Programs and Programming
Gene Interaction
Deviation, Epistatic
Single Nucleotide Polymorphism
EAF2 gene
1
8
Paper Details
References
  • References26
  • Citations4
123
  • References26
  • Citations4
1

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Gene-Gene Interactions Detection Using a Two-stage Model

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology

Apr 15, 2015

Zhanyong WangEleazar Eskin

PMID: 25871811

DOI: 10.1089/cmb.2014.0163

Abstract

Genome-wide association studies (GWAS) have discovered numerous loci involved in genetic traits. Virtually all studies have reported associations between individual single nucleotide polymorphisms (SNPs) and traits. However, it is likely that complex traits are influenced by interaction...read more

Mentioned in this Paper

Biological Markers
Genome-Wide Association Study
Study
Laboratory Procedures
Joints
Computer Programs and Programming
Gene Interaction
Deviation, Epistatic
Single Nucleotide Polymorphism
EAF2 gene
1
8

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Source Code for Biology and Medicine

Tools for efficient epistasis detection in genome-wide association study

Source Code for Biology and MedicineJanuary 6, 2011
Xiang ZhangWei Wang
Genetics Research

Genome-wide interaction analysis of quantitative traits in outbred mice

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Paper Details
References
  • References26
  • Citations4
123
  • References26
  • Citations4
1
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