Gene Regulation: Stable Noise

Current Biology : CB
Jonathan R Chubb

Abstract

Transcriptional regulation is noisy, yet despite this variability, embryonic development reproducibly generates form and function. Recent work demonstrates that patterns of transcriptional activity in embryos are stably inherited through mitosis. These observations have implications for how accuracy arises in development.

References

Feb 1, 1995·Current Opinion in Cell Biology·K A Giuliano, D L Taylor
Jul 17, 2007·Cell·Thomas GregorWilliam Bialek
Aug 28, 2010·Current Biology : CB·Michael W PerryMichael Levine
Mar 19, 2011·Cell·Gábor BalázsiJames J Collins
Mar 14, 2012·EMBO Reports·Timothée Lionnet, Robert H Singer
Sep 27, 2012·Molecular Systems Biology·Lei ZhangQing Nie
May 28, 2013·Cell·Mounia LaghaMichael S Levine
Jan 7, 2014·Current Biology : CB·Adam M Corrigan, Jonathan R Chubb
Jan 11, 2016·Current Biology : CB·Teresa FerraroMounia Lagha

❮ Previous
Next ❯

Citations

Dec 30, 2017·Nucleus·Evgeny SmirnovIvan Raška
Feb 23, 2020·Scientific Reports·Michael WilkinsonGreg Huber
Mar 3, 2020·PloS One·Evgeny SmirnovDušan Cmarko
Aug 19, 2017·Biology of Sex Differences·Rachael J WernerNora Engel
Nov 13, 2020·Physical Biology·Anissa Guillemin, Michael P H Stumpf
Mar 17, 2021·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Neda Barzgar BaroughKobra Velaei

❮ Previous
Next ❯

Related Concepts

Related Feeds

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Actin, Myosin & Cell Movement

Contractile forces generated by the actin-myosin cytoskeleton are critical for morphogenesis, but the cellular and molecular mechanisms of contraction have been elusive for many cell shape changes and movements. Here is the latest research on the roles of actin and myosin in cell movement.

© 2021 Meta ULC. All rights reserved