Gene regulatory divergence between locally adapted ecotypes in their native habitats

Molecular Ecology
Billie A GouldDavid B Lowry

Abstract

Local adaptation is a key driver of ecological specialization and the formation of new species. Despite its importance, the evolution of gene regulatory divergence among locally adapted populations is poorly understood, especially how that divergence manifests in nature. Here, we evaluate gene expression divergence and allele-specific gene expression responses for locally adapted coastal perennial and inland annual accessions of the yellow monkeyflower, Mimulus guttatus, in a field reciprocal transplant experiment. Overall, 6765 (73%) of surveyed genes were differentially expressed between coastal and inland habitats, while 7213 (77%) were differentially expressed between the coastal perennial and inland annual accessions. Cis-regulatory variation was pervasive, affecting 79% (5532) of differentially expressed genes. We detected trans effects for 52% (3611) of differentially expressed genes. Expression plasticity of alleles across habitats (G × E interactions) appears to be relatively common (affecting 18% of transcripts) and could minimize fitness trade-offs at loci that contribute to local adaptation. We also found evidence that at least one chromosomal inversion may act as supergene by holding together haplotypes of differen...Continue Reading

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Citations

Nov 18, 2018·The Plant Journal : for Cell and Molecular Biology·Maricris L ZaidemMichael D Purugganan
Dec 14, 2019·Molecular Ecology·Mariana Vargas CruzAnete Pereira de Souza
Feb 23, 2020·Molecular Biology and Evolution·Katy MorganLeslie M Turner
Jun 18, 2020·G3 : Genes - Genomes - Genetics·Jaakko S TyrmiTanja Pyhäjärvi
Dec 4, 2020·PLoS Genetics·Taylor CrowDaniel Runcie
Feb 16, 2021·Journal of Systematics and Evolution·Jill Anderson, Bao-Hua Song
Dec 12, 2020·Applications in Plant Sciences·Hannah E MarxKatrina M Dlugosch
Apr 11, 2021·Journal of Evolutionary Biology·Kevin M JohnsonMorgan W Kelly

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