journal cover

Gene size matters: What determines gene length in the human genome?

bioRxiv

Jan 10, 2020

Inês LopesJoao Pedro de Magalhaes

Abstract

While it is expected for gene length to be influenced by factors such as intron number and evolutionary conservation, we have yet to fully understand the connection between gene length and function in the human genome. In this study, we show that, as expected, there is a strong positive...read more

Mentioned in this Paper

Analysis
Immune Response
Skin
Neurodegenerative Disorders
Neurons
Malignant Neoplasms
Protein-Protein Interaction
Stomach
Introns
Blood Vessel
68
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Neurodegeneration: Genetics

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.

Neurotoxicity, Inflammation & Neuroprotection

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest discoveries pertaining to neurotoxicity, inflammation and neuroprotection.

Organelles in Neurodegeneration

Neurodegeneration is the progressive loss of neural structures and functions, including neuronal death. This feed focuses on dynamics of neuronal organelles in neurodegenerative diseases.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Innate Immunity: Neurodegeneration

The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.

Neurogenetic Disorders

Neurogenetic disorders are caused by a defect in one or more genes affecting the differentiation and function of the neuroectoderm and its derivatives. Here is the latest research on neurogenetic disorders

Neurotoxicity, Inflammation & Neuroprotection (Preprints)

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest preprints pertaining to neurotoxicity, inflammation and neuroprotection.

Tumor Evasion of the Immune System

Tumor evasion of the immune system includes cells that operate their own growth and develop various strategies to escape from immune surveillance. Discover the latest research on tumor evasion of the immune system here.

Human Tumor Atlas (Preprints)

The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments. Discover the latest preprints from the Human Tumor Atlas here.

Cancer Genomics (Preprints)

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

Hypothalamic Vasculature

The interrelationship of hypothalamic neurons and pituitary cells with the vasculature is important role for regulating the pattern of neurohormone exposure. Discover new insights into hypothalamic vasculature with this feed.

Related Papers

The Journal of Obstetrics and Gynaecology of the British Empire

Spread to skin from cancer of the cervix uteri; report of a case

The Journal of Obstetrics and Gynaecology of the British EmpireFebruary 1, 1957
J M FULLERTON, M SALMOND
© 2020 Meta ULC. All rights reserved

Gene size matters: What determines gene length in the human genome?

bioRxiv

Jan 10, 2020

Inês LopesJoao Pedro de Magalhaes

DOI: 10.1101/2020.01.10.901272

Abstract

While it is expected for gene length to be influenced by factors such as intron number and evolutionary conservation, we have yet to fully understand the connection between gene length and function in the human genome. In this study, we show that, as expected, there is a strong positive...read more

Mentioned in this Paper

Analysis
Immune Response
Skin
Neurodegenerative Disorders
Neurons
Malignant Neoplasms
Protein-Protein Interaction
Stomach
Introns
Blood Vessel
68

Similar Papers Found In These Feeds

Neurodegeneration: Genetics

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.

Neurotoxicity, Inflammation & Neuroprotection

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest discoveries pertaining to neurotoxicity, inflammation and neuroprotection.

Related Papers

The Journal of Obstetrics and Gynaecology of the British Empire

Spread to skin from cancer of the cervix uteri; report of a case

The Journal of Obstetrics and Gynaecology of the British EmpireFebruary 1, 1957
J M FULLERTON, M SALMOND
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/gene-size-matters-what-determines-gene-length-in/990901272