General CuBr2-catalyzed highly enantioselective approach for optically active allenols from terminal alkynols

Chemical Communications : Chem Comm
Xin HuangShengming Ma

Abstract

Here, we show a CuBr2-catalyzed approach for a highly enantioselective synthesis (93-99% ee) of allenols from aldehydes and terminal alkynols with the absolute configuration being controlled by applying readily available (R)- or (S)-α,α-diphenylprolinol.

References

Mar 3, 2004·Angewandte Chemie·Anja Hoffmann-Röder, Norbert Krause
Oct 13, 2005·Journal of the American Chemical Society·Barry M TrostDiana C Dinh
Dec 16, 2005·Organic Letters·Yasushi ImadaTakeshi Naota
Mar 28, 2006·Organic Letters·Ricardo RiveirosLuis A Sarandeses
Jan 28, 2010·Journal of the American Chemical Society·Jinqiang Kuang, Shengming Ma
Mar 17, 2011·Chemical Communications : Chem Comm·Shichao Yu, Shengming Ma
Jan 25, 2012·Angewandte Chemie·Shichao Yu, Shengming Ma
Sep 11, 2012·Angewandte Chemie·Baoqiang Wan, Shengming Ma
Nov 13, 2012·Chemistry : a European Journal·Juntao YeShengming Ma
Feb 21, 2013·Nature Chemistry·Takuya HashimotoKeiji Maruoka
Mar 16, 2013·Journal of the American Chemical Society·Ian T CrouchDoug E Frantz
Apr 24, 2013·Organic Letters·Ruizhi LüShengming Ma
Jul 23, 2013·Journal of the American Chemical Society·Yuli WangShengming Ma
Mar 6, 2015·Organic & Biomolecular Chemistry·Jiasheng ZhangShengming Ma

❮ Previous
Next ❯

Citations

Jun 16, 2016·Journal of the American Chemical Society·Xingguo JiangShengming Ma
Jul 13, 2016·Chemistry : a European Journal·Xiaojun Huang, Alejandro Bugarin
Jul 13, 2017·The Journal of Organic Chemistry·Maren Schaarschmidt, Klaus T Wanner
Apr 24, 2019·Chemistry : a European Journal·Jing ZhouShengming Ma
Nov 20, 2016·Chemistry : a European Journal·Stacey WebsterAi-Lan Lee
Mar 16, 2018·Chemistry : a European Journal·Daniel R SutherlandAi-Lan Lee
Mar 8, 2019·Chemical Science·Yifan CuiShengming Ma
Feb 2, 2019·Nature Communications·Shihua SongShengming Ma
Mar 31, 2021·Organic Letters·Jun Li, Scott R Gilbertson
Apr 16, 2019·Accounts of Chemical Research·Xin Huang, Shengming Ma
Sep 23, 2021·ACS Omega·Leandros P ZorbaGeorgios C Vougioukalakis
Oct 2, 2021·Angewandte Chemie·Junzhe XiaoShengming Ma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.