General-purpose genotype or how epigenetics extend the flexibility of a genotype.

Genetics Research International
Rachel Massicotte, Bernard Angers

Abstract

This project aims at investigating the link between individual epigenetic variability (not related to genetic variability) and the variation of natural environmental conditions. We studied DNA methylation polymorphisms of individuals belonging to a single genetic lineage of the clonal diploid fish Chrosomus eos-neogaeus sampled in seven geographically distant lakes. In spite of a low number of informative fragments obtained from an MSAP analysis, individuals of a given lake are epigenetically similar, and methylation profiles allow the clustering of individuals in two distinct groups of populations among lakes. More importantly, we observed a significant pH variation that is consistent with the two epigenetic groups. It thus seems that the genotype studied has the potential to respond differentially via epigenetic modifications under variable environmental conditions, making epigenetic processes a relevant molecular mechanism contributing to phenotypic plasticity over variable environments in accordance with the GPG model.

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Citations

Nov 22, 2013·Proceedings. Biological Sciences·Lynn B MartinAaron W Schrey
May 9, 2012·Genetics Research International·Emilie Castonguay, Bernard Angers
Jan 15, 2014·Evolution; International Journal of Organic Evolution·Carl D Schlichting, Matthew A Wund
Nov 28, 2013·Evolution; International Journal of Organic Evolution·Koen J F Verhoeven, Veronica Preite
Jun 4, 2014·Journal of Fish Biology·H Joensen, O Grahl-Nielsen
Aug 24, 2016·Ecology and Evolution·Christelle LeungBernard Angers
Jun 10, 2017·Journal of Evolutionary Biology·J Hu, R D H Barrett
Dec 7, 2018·Environmental Epigenetics·France Beauregard, Bernard Angers
May 30, 2020·Integrative and Comparative Biology·C BiwerF Silvestre
Jul 21, 2020·Evolutionary Applications·Bernard AngersChristelle Leung
Jul 4, 2016·Environmental Epigenetics·Aaron W SchreyTracy Langkilde
Aug 15, 2019·Ecology and Evolution·Waldir M Berbel-FilhoSofia Consuegra
Mar 19, 2019·Frontiers in Plant Science·Wen ShiYupeng Geng
Nov 1, 2020·Epigenetics : Official Journal of the DNA Methylation Society·Delphine LalliasMathilde Dupont-Nivet

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Methods Mentioned

BETA
PCR

Software Mentioned

MSAP

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