PMID: 9658010Jul 11, 1998Paper

General stress transcription factor sigmaB and its role in acid tolerance and virulence of Listeria monocytogenes

Journal of Bacteriology
Martin WiedmannKathryn J Boor

Abstract

The gene encoding the general stress transcription factor sigmaB in the gram-positive bacterium Listeria monocytogenes was isolated with degenerate PCR primers followed by inverse PCR amplification. Evidence for gene identification includes the following: (i) phylogenetic analyses of reported amino acid sequences for sigmaB and the closely related sigmaF proteins grouped L. monocytogenes sigmaB in the same cluster with the sigmaB proteins from Bacillus subtilis and Staphylococcus aureus, (ii) the gene order in the 2, 668-bp portion of the L. monocytogenes sigB operon is rsbU-rsbV-rsbW-sigB-rsbX and is therefore identical to the order of the last five genes of the B. subtilis sigB operon, and (iii) an L. monocytogenes sigmaB mutant had reduced resistance to acid stress in comparison with its isogenic parent strain. The sigB mutant was further characterized in mouse models of listeriosis by determining recovery rates of the wild-type and mutant strains from livers and spleens following intragastric or intraperitoneal infection. Our results suggest that sigmaB-directed genes do not appear to be essential for the spread of L. monocytogenes to mouse liver or spleen at 2 and 4 days following intragastric or intraperitoneal infection.

References

Dec 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·F C FangD G Guiney
Jun 1, 1992·Journal of Bacteriology·M LonettoC A Gross
Feb 1, 1992·Journal of Bacteriology·A K Benson, W G Haldenwang
Jun 11, 1991·Journal of Bacteriology·T J Kenney, C P Moran
Oct 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·D DanielsR Losick
Sep 20, 1990·Journal of Molecular Biology·C WaldburgerM M Susskind
Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Apr 20, 1989·Journal of Molecular Biology·P ZuberR Losick
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·T J KenneyC P Moran
Apr 20, 1989·Journal of Molecular Biology·T GardellaM M Susskind
Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·C BinnieR Losick
Jan 1, 1988·Annual Review of Biochemistry·J D Helmann, M J Chamberlin
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·W G Haldenwang, R Losick
Mar 1, 1995·Microbiological Reviews·W G Haldenwang
Jan 1, 1994·Annual Review of Microbiology·P C Loewen, R Hengge-Aronis
Apr 1, 1994·Journal of Bacteriology·A Dufour, W G Haldenwang
Dec 1, 1993·Journal of Bacteriology·S A BoylanC W Price
Apr 1, 1993·Journal of Bacteriology·A K Benson, W G Haldenwang
Mar 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·A K Benson, W G Haldenwang
Apr 2, 1996·Proceedings of the National Academy of Sciences of the United States of America·J DeMaioW R Bishai

❮ Previous
Next ❯

Citations

Nov 28, 2000·Journal of Bacteriology·S GertzM Hecker
Mar 28, 2002·Applied and Environmental Microbiology·Yumiko OkadaShouji Yamazaki
Nov 15, 2002·Journal of Food Protection·Sophia Kathariou
May 27, 2005·Journal of Applied Microbiology·C G M Gahan, C Hill
Dec 13, 2005·Microbiology and Molecular Biology Reviews : MMBR·Mark J KazmierczakKathryn J Boor
Aug 4, 2006·Applied and Environmental Microbiology·Soraya Chaturongakul, Kathryn J Boor
Jul 1, 2008·Applied and Environmental Microbiology·Ioanna M Barmpalia-DavisJohn N Sofos
Nov 19, 2008·Foodborne Pathogens and Disease·Sara R Milillo, Martin Wiedmann
Jun 23, 2009·Microbiology·Roy D SleatorCormac G M Gahan
Feb 25, 2009·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Y OkadaS Igimi
Sep 6, 2011·Applied and Environmental Microbiology·Marta UtratnaConor P O'Byrne
Nov 19, 2011·FEMS Microbiology Letters·Moira MadeoConor P O'Byrne
Dec 25, 2012·International Journal of Molecular Sciences·Sana MujahidMartin Wiedmann
Nov 30, 2012·Archives of Microbiology·Zaichao ZhangLijuan Zhang
Apr 2, 2014·Infection and Immunity·Azad EshghiMathieu Picardeau
May 22, 2016·Applied and Environmental Microbiology·Claudia GuldimannVeronica Guariglia-Oropeza
Apr 9, 2016·Foodborne Pathogens and Disease·Sirirak Supa-AmornkulSoraya Chaturongakul
Jun 18, 2002·Infection and Immunity·Celine A NadonKathryn J Boor
Nov 9, 2002·FEMS Microbiology Letters·Nora HalgasovaJan Kormanec
Sep 3, 2003·Molecular Microbiology·Chien-Cheng ChenOlivier Delumeau
Oct 27, 2001·Molecular Microbiology·M Lalic-MülthalerW Goebel
Dec 12, 2007·Letters in Applied Microbiology·E M RyanC Hill

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.