PMID: 2899493Jun 1, 1988

Generalized convulsions in a patient receiving ultrashort-acting beta-blocker infusion

Drug Intelligence & Clinical Pharmacy
G Das, J C Ferris

Abstract

Beta-receptor blocking agents are commonly used to treat patients with heart disease, and generalized seizures due to therapy with these agents are rare. All reported cases of seizures due to beta blocking agents have occurred only in those subjects who ingested large doses of the drugs. We observed generalized convulsions in a patient who was receiving therapeutic doses of an ultrashort-acting beta-blocking agent (esmolol hydrochloride) intravenously. A literature survey and possible mechanisms by which these agents induce seizures are presented.

References

Feb 1, 1985·Annals of Emergency Medicine·R S WeinsteinT Dahlbert
Dec 1, 1984·Annals of Emergency Medicine·R S Weinstein
Jan 1, 1983·Acta Medica Scandinavica·C J Wallin, J Hulting
Jan 1, 1980·Archives of Toxicology·M Montagna, A Groppi

Citations

Jan 1, 1996·Journal of Toxicology. Clinical Toxicology·D M ReithG P Sayer
Jun 21, 2014·Pharmacological Reports : PR·Kinga K Borowicz, Monika Banach
Apr 8, 2020·Acta Neurologica Scandinavica·Gaetano ZaccaraEmilio Russo

Related Concepts

Esmolol hydrochloride
Adrenergic beta-Antagonists
Diastolic Blood Pressure
Propanolamines
Non-epileptic Convulsion

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