Generalized multiple-layer appearance of the cerebral cortex with 3D FLAIR 7.0-T MR imaging

Radiology
Jaco J M ZwanenburgPeter R Luijten

Abstract

To examine the multiple-layer appearance of the cerebral cortex with fluid-attenuated inversion recovery (FLAIR) magnetic resonance (MR) imaging at 7.0 T, whole-brain volumetric three-dimensional (3D) magnetization prepared FLAIR images were acquired in 12 volunteers (0.8 3 0.8 3 0.8-mm spatial resolution). Signal intensity profiles were evaluated for the anterior frontal (Brodmann area [BA] 10), posterior frontal (BA 6), parietal (BA 7), precentral (BA 4), postcentral (BA 3), occipital (BA 18), and calcarine (BA 17) regions. Variance of the normalized profile was used as the metric for the multiple-layer appearance. Wilcoxon signed-rank tests were performed to compare variances of the profiles between all areas. All cortical areas showed multiple-layered appearances, with a prominent hyperintense band at the external surface of the cortex, a hypointense band deeper in the cortex, and a hyperintense third band. The ranking from least- to most-pronounced layer appearance was as follows: postcentral (variance, 0.04), posterior frontal (variance, 0.05), calcarine (variance, 0.05), precentral (variance, 0.06), parietal (variance, 0.08), anterior frontal (variance, 0.10), and occipital (variance, 0.11). Each region was significantly...Continue Reading

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Citations

Oct 9, 2012·AJNR. American Journal of Neuroradiology·I D KilsdonkM P Wattjes
Jul 1, 2013·PET Clinics·Jaco J M ZwanenburgPeter R Luijten
Mar 13, 2015·NMR in Biomedicine·Wietske van der ZwaagRobert Trampel
Jan 9, 2014·Journal of Magnetic Resonance Imaging : JMRI·John P Mugler
Nov 2, 2013·NeuroImage. Clinical·Susanne J van VeluwGeert Jan Biessels
Sep 14, 2013·Radiology·Sanneke van RoodenJeroen van der Grond
Oct 16, 2014·NeuroImage·Susanne J van VeluwJaco J M Zwanenburg
Apr 26, 2017·NeuroImage·José P Marques, David G Norris

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