PMID: 590280Nov 4, 1977

Generalized oedema of newborn associated with the administration of dipyrone

European Journal of Pediatrics
M BajoghliM Gharavi


In fourteen infants, aged 9--60 days, with generalized oedema seen during a one year period the common denominator was the administration of dipyrone one to two days prior to the development of oedema. None of the other causes of oedema in early life could be incriminated in any of these babies. Pediatricians should be aware of this iatrogenic cause whenever they encounter a young infant with generalized oedema. Oedema disappeared in all the cases following discontinuation of dipyrone but anuria lasted for more than four days in one case. This stydy re-emphasizes the need to without this potentially dangerous drug, especially during the neonatal period.


Sep 1, 1976·The Journal of Pediatrics·J WiggelinkhuizenR O Kaschula
Jan 27, 1975·JAMA : the Journal of the American Medical Association·C A Ries, M A Sahud
Nov 28, 1968·The New England Journal of Medicine·J H RitchieM Grossman
Sep 21, 1964·JAMA : the Journal of the American Medical Association·C M HUGULEY


Dec 1, 1984·Human Toxicology·G Rizzoni, M Furlanut

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