Generalized posterior keratoconus: clinical pathologic correlations

Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Devesh K VarmaHamidreza Faraji

Abstract

A 73-year-old woman presented with bilateral generalized posterior keratoconus. The corneal thickness measured 0.320 mm paracentrally and 0.440 mm toward the periphery. The corneal specimen revealed absence of Bowman's layer and focal homogeneous oval stromal deposits that stained for amyloid. Our case of generalized posterior keratoconus shows absence of Bowman's layer. The amyloid deposits, which also were noted clinically in the cornea of the fellow right eye, were most consistent with a diagnosis of polymorphous amyloid degeneration. To our knowledge, this is the first histopathological report of generalized posterior keratoconus.

References

Oct 1, 1978·Archives of Ophthalmology·J H Krachmer, M M Rodrigues
Apr 1, 1983·Archives of Ophthalmology·B W StreetenK H Spitzer
Mar 1, 1963·Archives of Ophthalmology·J R WOLTER, W P HANEY
Jun 9, 2004·American Journal of Ophthalmology·Jay W McLarenWilliam M Bourne

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Citations

Nov 11, 2017·The British Journal of Ophthalmology·Megan R SilasAsim V Farooq
Aug 25, 2020·Cornea·Niruban GanesanMuthukrishnan Vallinayagam

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