PMID: 11847089Feb 16, 2002

Generating samples under a Wright-Fisher neutral model of genetic variation

Bioinformatics
Richard R Hudson

Abstract

A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.

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Related Concepts

Computer Software
Polaron
Genetics, Population
Recombination, Genetic
Computer Programs and Programming
Monte Carlo Method
Gene Conversion
Mutation Abnormality
Computational Molecular Biology
Variation (Genetics)

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