Generation of benzoimidazo[1,5-a]imidazoles via a copper-catalyzed tandem reaction of carbodiimide and isocyanoacetate

Chemical Communications : Chem Comm
Guanyinsheng Qiu, Jie Wu

Abstract

Carbodiimide reacts with isocyanide catalyzed by copper(i) iodide, leading to benzoimidazo[1,5-a]imidazoles in good yields. This reaction is efficient, and proceeds through a formal [3+2] cycloaddition and C-N coupling.

References

Oct 12, 2000·Angewandte Chemie·A Dömling, I Ugi
Dec 16, 2003·Research in Veterinary Science·J VelíkL Skálová
Jan 27, 2005·Chemical Communications : Chem Comm·Kimihiro KomeyamaKen Takaki
Aug 17, 2006·Journal of the American Chemical Society·Chikashi KanazawaYoshinori Yamamoto
Nov 10, 2006·Chemical Reviews·Gilson Zeni, Richard C Larock
Jun 20, 2007·Chemical Society Reviews·Ana Minatti, Kilian Muñiz
Aug 28, 2007·Journal of the American Chemical Society·Mamoru TobisuNaoto Chatani
Jul 18, 2008·Chemical Reviews·Míriam Alvarez-CorralIgnacio Rodríguez-García
Aug 14, 2008·Accounts of Chemical Research·Dawei Ma, Qian Cai
Nov 26, 2008·Chemistry : a European Journal·Alexander V LyginArmin de Meijere
Aug 15, 2009·Angewandte Chemie·Florian Monnier, Marc Taillefer
Sep 10, 2009·Chemical Reviews·Marcos A P MartinsPablo Machado
Oct 6, 2009·Chemical Reviews·Alan R Katritzky, Stanislaw Rachwal
Jul 9, 2010·Chemical Reviews·Anton V GulevichValentine G Nenajdenko
Jun 29, 2011·Angewandte Chemie·Eelco RuijterRomano V A Orru
Oct 6, 2011·Chemistry : a European Journal·Chen ZhuJohn R Falck
Nov 17, 2011·Organic Letters·Tjøstil VlaarRomano V A Orru
Nov 30, 2011·Chemistry : a European Journal·Gitte Van BaelenRomano V A Orru
Feb 9, 2012·Chemical Communications : Chem Comm·Guanyinsheng QiuJie Wu
Feb 14, 2012·Organic Letters·Takahiro SoetaYutaka Ukaji
Feb 24, 2012·Organic Letters·Fabio De Moliner, Christopher Hulme
Mar 21, 2012·Chemical Communications : Chem Comm·Jiangling PengQiang Zhu

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Citations

Aug 17, 2016·The Journal of Organic Chemistry·Georgette CastanedoMarie-Gabrielle Braun
Sep 10, 2016·The Journal of Organic Chemistry·Danqing ZhengJie Wu
Dec 9, 2014·Advanced Synthesis & Catalysis·Suravi ChakrabartyFraser F Fleming
Mar 6, 2015·Chemical Reviews·Vadim P BoyarskiyVadim Yu Kukushkin

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