Genes and chromosomes: control of development

Anais Da Academia Brasileira De Ciências
O L Serov, Irina Serova

Abstract

The past decade has witnessed immense progress in research into the molecular basis behind the developmental regulation of genes. Sets of genes functioning under hierarchical control have been identified, evolutionary conserved systems of genes effecting the cell-to-cell transmission of transmembrane signals and assigned a central role in morphogenesis have been intensively studied; the concept of genomic regulatory networks coordinating expression of many genes has been introduced, to mention some of the major breakthroughs. It should be noted that the temporal and tissue-specific parameters of gene expression are correctly regulated in development only in the context of the chromosome and that they are to a great extent dependent on the position of the gene on the chromosome or the interphase nucleus. Moreover epigenetic inheritance of the gene states through successive cell generations has been conducted exclusively at the chromosome level by virtue of cell or chromosome memory. The ontogenetic memory is an inherent property of the chromosome and cis-regulation has a crucial role in its maintenance.

References

Jan 1, 1979·International Review of Cytology. Supplement·J B GurdonG A Partington
Oct 1, 1992·Developmental Dynamics : an Official Publication of the American Association of Anatomists·I S ThoreyR G Oshima
Jan 1, 1986·Journal of Cell Science. Supplement·J B Gurdon
Jan 1, 1986·Annual Review of Genetics·R D Palmiter, R L Brinster
Jul 1, 1984·Cell·K D TartofM Jones
Jun 6, 1995·Proceedings of the National Academy of Sciences of the United States of America·G RobertsonE Whitelaw
Jun 25, 1996·Proceedings of the National Academy of Sciences of the United States of America·K W DobieM McClenaghan
Jan 1, 1995·Annual Review of Genetics·K S Weiler, B T Wakimoto
Nov 14, 1997·Advances in Genetics·I F Zhimulev
Dec 6, 1997·Current Opinion in Genetics & Development·D Kioussis, R Festenstein
Jan 13, 1998·Nature Genetics·D GarrickE Whitelaw
May 20, 1998·Current Biology : CB·D Zink, T Cremer
Jul 11, 1998·Molecular Cell·N DillonF Grosveld
Feb 13, 1999·Cell·B L Hogan
May 14, 1999·Current Opinion in Genetics & Development·M Cockell, S M Gasser
Jun 15, 1999·The Journal of Cell Biology·J A CroftW A Bickmore
Aug 12, 1999·Seminars in Cell & Developmental Biology·J B Gurdon
Sep 24, 1999·International Review of Cytology·K E Latham
Sep 25, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·F Lyko, R Paro
Oct 16, 1999·Science·S J O'BrienJ A Marshall Graves
Oct 16, 1999·Science·A P Wolffe, M A Matzke
Nov 24, 1999·The EMBO Journal·T ZhumaD Kioussis
Mar 25, 2000·Science·M D AdamsJ C Venter
Jun 27, 2000·Biophysical Journal·H B SunH Yokota
Sep 6, 2000·Genes & Development·B S CobbS T Smale
Sep 27, 2000·Evolution; International Journal of Organic Evolution·D L Stern
Dec 29, 2000·Nature·UNKNOWN Arabidopsis Genome Initiative
Mar 10, 2001·Molecular Reproduction and Development·T Wakayama, R Yanagimachi
Apr 17, 2001·Science·K A GussS B Carroll
Aug 11, 2001·Science·W M RideoutR Jaenisch
Sep 13, 2001·Biochimica Et Biophysica Acta·P EdelmannC Cremer

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Citations

Jul 11, 2012·BMC Plant Biology·Junhua LiChangbin Chen

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