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Genes in the terminal regions of orthopoxvirus genomes experience adaptive molecular evolution

BMC Genomics

May 23, 2011

David J Esteban, Anne P Hutchinson

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Abstract

Orthopoxviruses are dsDNA viruses with large genomes, some encoding over 200 genes. Genes essential for viral replication are located in the center of the linear genome and genes encoding host response modifiers and other host interacting proteins are located in the terminal regions. Th...read more

Mentioned in this Paper

Smallpox Viruses
Enzymes, antithrombotic
Amino Acid [EPC]
Enzymes, peripheral vasodilators
Interferon
Homologous Gene
Cell Surface
IL18 gene
Interleukin-18
Recombinant Interleukin-18
Paper Details
References
  • References47
  • Citations11
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Genes in the terminal regions of orthopoxvirus genomes experience adaptive molecular evolution

BMC Genomics

May 23, 2011

David J Esteban, Anne P Hutchinson

PMID: 21605412

DOI: 10.1186/1471-2164-12-261

Abstract

Orthopoxviruses are dsDNA viruses with large genomes, some encoding over 200 genes. Genes essential for viral replication are located in the center of the linear genome and genes encoding host response modifiers and other host interacting proteins are located in the terminal regions. Th...read more

Mentioned in this Paper

Smallpox Viruses
Enzymes, antithrombotic
Amino Acid [EPC]
Enzymes, peripheral vasodilators
Interferon

Similar Papers Found In These Feeds

Paper Details
References
  • References47
  • Citations11
12

Get paper from

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