Genetic analysis of 39 Y-STR loci in a Han population from Henan province, central China

International Journal of Legal Medicine
Yanmei HuangHongyu Sun

Abstract

A total of 39 Y-chromosomal short tandem repeat (Y-STR) loci included in the advanced commercial six-dye multiplex system (AGCU Database Y30 kit) and a custom-designed four-dye multiplex system were investigated in 259 unrelated healthy Chinese males residing in Henan Province, central China. The haplotype diversity (HD) values were 0.99997 and 1.0000 for the six and four fluorescent-multiplex amplification systems, respectively. The discrimination capacity (DC) values were 0.9961 and 1.0000, respectively. When the 39 Y-STR loci were considered, 259 unique haplotypes were obtained in Henan Han individuals with both the haplotype diversity and discrimination capacity being 1.000. The gene diversity (GD) of 39 Y-STR loci in the studied group ranged from 0.3956 (DYS588) to 0.9990 (DYF403S1). Population comparisons between the Henan Han and 24 reference groups were performed. Both multidimensional scaling plots and phylogenetic analysis demonstrated that significant genetic differences existed between Henan Han and reference ethnic minorities of China, particularly the Tibetan, Uighur, and Mongolian populations. Moreover, the results indicated that 39 Y-STRs included in the two fluorescent-multiplex amplification systems are highly...Continue Reading

References

Oct 5, 2010·Forensic Science International. Genetics·M E D'AmatoS Davison
May 27, 2011·Forensic Science International. Genetics·Kaye N BallantyneManfred Kayser
Jun 12, 2014·Human Mutation·Kaye N BallantyneManfred Kayser
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Mar 21, 2017·Human Genetics·Manfred Kayser
May 4, 2017·International Journal of Legal Medicine·Rashed AlghafriPankaj Shrivastava

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