Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection

Microbes and Infection
George S YapA Sher

Abstract

Cell-mediated immunity to Toxoplasma gondii establishes and maintains a balanced host-pathogen relationship. Recent analyses using spontaneous and genetically engineered mouse mutants have yielded a clearer picture of factors positively and negatively regulating the host immune response and a better understanding of cytokine-inducible intracytoplasmic mechanisms that lead to intracellular pathogen suppression and demise.

References

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Citations

Jul 22, 2008·Nature Reviews. Immunology·Jatin M VyasHidde L Ploegh
Oct 13, 2011·The Journal of Infectious Diseases·Senad DivanovicChristopher L Karp
Jul 9, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Marcos FloresMiriam Rodriguez-Sosa
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Jun 29, 2010·Trends in Parasitology·Fiona L HenriquezCraig W Roberts
Sep 9, 2008·International Journal for Parasitology·Catherine M MillerNicholas C Smith
Jun 3, 2008·Trends in Parasitology·Danièle MaubonHervé Pelloux
Nov 30, 2007·Immunology Letters·Fiona M MenziesCraig W Roberts
Nov 21, 2007·Microbes and Infection·Stephanie Könen-Waisman, Jonathan C Howard
Jan 16, 2008·Parasite Immunology·F S Dzierszinski, C A Hunter
Jul 21, 2011·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Sarah J Fentress, L David Sibley
Mar 7, 2006·Microbes and Infection·Tom H M Ottenhoff
Sep 9, 2017·PloS One·Kärt MustPikka Jokelainen
Oct 23, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tadakimi TomitaAmos Orlofsky

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