PMID: 9175258May 1, 1997Paper

Genetic and antigenic heterogeneity among feline calicivirus isolates from distinct disease manifestations

Virus Research
K GeisslerU Truyen

Abstract

The capsid protein genes of five feline calicivirus (FCV) isolates associated with different disease manifestations were cloned and sequenced. The viruses represented two recent isolates from cats with chronic stomatitis, one recent isolate from a cat with acute stomatitis, one recent isolate each from a cat with acute respiratory symptoms and the classical limping syndrome strain FCV-2280. The amino acid sequences were compared with eight other published sequences and analyzed for their relationships. Phylogenetic analysis of the complete capsid protein sequences or of known antigenic regions of that protein (hypervariable regions A and E) did not group the isolates of different disease manifestations in distinct subclusters. Monoclonal antibodies (MAbs) generated against either a chronic stomatitis isolate or a recent isolate associated with respiratory symptoms were tested against a panel of 11 recent isolates and four "classical' FCV strains, covering all known disease associations. With those MAbs no obvious clustering with respect to disease manifestation could be seen. Four specific sera prepared in rabbits against our prototype isolates also failed to cluster those isolates according to the disease manifestations when e...Continue Reading

References

Sep 1, 1992·The Journal of General Virology·I D MiltonM J Carter
Sep 1, 1992·Virology·M J CarterP C Turner
May 1, 1991·Veterinary Microbiology·J O KnowlesR M Gaskell
Jan 1, 1991·Archives of Virology·Y TohyaT Mikami
Jun 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J L FuR P Roos
Mar 1, 1994·Research in Veterinary Science·S DawsonR M Gaskell
May 22, 2002·Journal of Virology·Philip J YoungChristian L Lorson
Apr 14, 2004·Journal of Virology·Tanaji MitraKim Y Green
Sep 1, 1995·Acta Crystallographica. Section D, Biological Crystallography·L Zhou, M Luo

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Citations

Mar 12, 2009·Parasitology Research·N MenckeU Truyen
Aug 13, 2003·The Veterinary Clinics of North America. Small Animal Practice·Kate F Hurley, Jane E Sykes
Feb 22, 2002·Veterinary Microbiology·Vito MartellaCanio Buonavoglia
Sep 29, 1999·Veterinary Microbiology·C Baulch-BrownJ Meanger
Mar 26, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·K GeisslerU Truyen
Jul 18, 2008·Journal of Virology·Kyeong-Ok ChangStanislav V Sosnovtsev
Jan 23, 2004·Journal of the American Veterinary Medical Association·Kate E HurleyJanet E Foley
Nov 3, 2006·Journal of the American Veterinary Medical Association·James R RichardsAndrew H Sparkes
May 27, 2008·The Veterinary Clinics of North America. Small Animal Practice·Patricia A PesaventoJohn S L Parker
Mar 27, 2007·Veterinary Microbiology·Cheol JeongKyoung-Oh Cho
Nov 28, 2006·Veterinary Microbiology·Barbara Di MartinoPolly Roy
Mar 26, 2003·Oral Microbiology and Immunology·M J Lommer, F J M Verstraete
Apr 16, 2004·Virus Research·Lilia Ganova-RaevaYury Khudyakov
May 16, 2006·Veterinary Microbiology·Alan D RadfordRosalind M Gaskell
Jun 28, 2005·The Veterinary Clinics of North America. Small Animal Practice·Kenneth F Lyon
Jun 20, 2001·The Journal of General Virology·Y MatsuuraT Sugimura
Jul 29, 1999·The Journal of Veterinary Medical Science·M HashimotoM Mochizuki
Oct 18, 2000·The Veterinary Clinics of North America. Small Animal Practice·D T Ramsey
Oct 27, 2016·Food and Environmental Virology·Eva EmmothFrederik Widén
Dec 3, 2016·The Journal of General Virology·Andrea M SpiriBarbara Willi
Jan 30, 2016·The Veterinary Record·Hervé Poulet
Nov 30, 2005·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Mohamed Abd-EldaimMelissa Kennedy
Feb 14, 2007·Veterinary Research·Alan D RadfordRosalind M Gaskell
May 3, 2020·Transboundary and Emerging Diseases·Barbara Di MartinoVito Martella
Aug 3, 2019·Viruses·Michèle BergmannKatrin Hartmann

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