PMID: 8939624Oct 1, 1996Paper

Genetic and biochemical probes for protein-protein interactions

Current Opinion in Biotechnology
D S McNabb, L Guarente

Abstract

The two-hybrid system is a powerful approach for examining protein-protein interactions. Recently, the utility of the system has been extended to include the genome-wide mapping of protein-protein interactions and the identification of peptide inhibitors of protein interactions. In addition, immunophilins and their chemical ligands are providing useful reagents for generating conditional protein-protein interactions in vivo to dissect intracellular signaling pathways.

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Citations

Aug 28, 1998·Trends in Biotechnology·P Colas, R Brent
Jul 17, 1998·Current Opinion in Biotechnology·G B Martin
Aug 1, 1997·Current Opinion in Structural Biology·P Kast, D Hilvert
Nov 14, 1997·Current Opinion in Biotechnology·R K Brachmann, J D Boeke
Jul 24, 2021·Chemical Reviews·Yajie WangHuimin Zhao

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