Genetic and environmental influences on infant sleep.

Pediatrics
Abigail FisherJane Wardle

Abstract

Sleep duration is attracting increasing attention in relation to chronic disease risk, but few large-scale studies have investigated the determinants of sleep characteristics in early life. In this study we used data from a large, population-based twin study to examine genetic and environmental influences on sleep duration and sleep difficulties in infancy. Participants were 1931 pairs of young twins (3862 children) from the Gemini twin birth cohort. Sleep patterns were assessed at 15 months by using a modification of the Brief Infant Sleep Questionnaire completed by parents. Outcomes included nighttime and daytime sleep duration and frequency of night waking. Twin analyses showed that nighttime sleep duration was predominantly influenced by the shared environment (66%, confidence interval [CI] 63%-70%) with a modest genetic effect (26%, CI 22%-30%). A similar pattern was observed for daytime nap duration (shared environment: 57%, CI 53%-62%; genetic effect: 37%, CI 33%-41%) and sleep disturbance (shared environment: 55%, 44%-64%) with a genetic effect of 40% (30%-51%). These estimates were similar for boys and girls. These results indicate an important contribution of the shared family environment as well as genes to children'...Continue Reading

Citations

Jun 6, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M ReymanH S Schipper
Feb 8, 2014·Annals of Nutrition & Metabolism·Nina E BerentzenHenriëtte A Smit
Mar 29, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A FisherJ Wardle
Jan 12, 2016·Behavioral Sleep Medicine·Sally L StatonKaren J Thorpe
Apr 9, 2015·Journal of Developmental and Behavioral Pediatrics : JDBP·Sally L StatonKaren J Thorpe
Jun 20, 2018·Nursing Science Quarterly·Elizabeth M Keys, Karen M Benzies
Sep 8, 2017·Journal of Clinical Nursing·Pei-Wen HsuShao-Yu Tsai
Jan 20, 2015·Infant and Child Development·Caroline H D Jones, Helen Ball
Jul 4, 2019·Chronobiology International·Anja KärkiSari-Leena Himanen
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Jan 8, 2021·Frontiers in Psychiatry·Susanne KnappeJulia Martini
Feb 23, 2020·Sleep Medicine·E Juulia PaavonenLinnea Karlsson
Feb 27, 2021·Sleep Medicine Reviews·Desana KocevskaEus J W Van Someren
May 6, 2021·The Journal of Genetic Psychology·Randi A BatesLaura M Justice
Aug 16, 2021·Infant Behavior & Development·Charles M SuperRucha Londhe
Aug 16, 2021·Infant Behavior & Development·Agnes G BuckoRussell R Pate
Sep 16, 2021·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Terje Falck-YtterAngelica Ronald

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