Genetic and nongenetic factors contributing to differences in αS -casein phosphorylation isoforms and other major milk proteins

Journal of Dairy Science
Z H FangP Martin

Abstract

Relative concentrations of αS-casein (αS-CN) phosphorylation isoforms vary considerably among milk of individual cows. We aimed to explore to what extent genetic and other factors contribute to the variation in relative concentrations of αS-CN phosphorylation isoforms and the phosphorylation degree of αS-CN defined as the proportion of isoforms with higher degrees of phosphorylation. We also investigated the associations of genetic variants of milk proteins and casein haplotypes with relative concentrations of αS-CN phosphorylation isoforms and with the phosphorylation degree of αS-CN in French Montbéliarde cattle from the cheese production area of Franche-Comté. Detailed milk protein composition was determined by liquid chromatography coupled with electrospray ionization mass spectrometry from 531 test-day morning milk samples. Parity, lactation stage, and genetic variation of cows contributed to the phenotypic variation in relative concentrations of individual αS-CN phosphorylation isoforms and in the phosphorylation degree of αS-CN. As lactation progressed, we observed a significant increase for relative concentrations of αS-CN isoforms with higher degrees of phosphorylation (αS1-CN-9P, αS2-CN-13P, and αS2-CN-14P) as well as...Continue Reading

References

Mar 28, 2008·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·E HallénA Lundén
Feb 24, 2009·Journal of Dairy Science·G C B SchopenJ A M van Arendonk
Feb 24, 2009·Journal of Dairy Science·J M L HeckA C M van Hooijdonk
Mar 28, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Robert F Gilmour
Jan 27, 2012·BMC Genomics·Saumya WickramasingheJuan F Medrano
May 8, 2014·Current Biology : CB·Maria M Magiera, Carsten Janke
Sep 10, 2014·Journal of Dairy Science·E BijlH Bovenhuis
Jul 6, 2015·Journal of Dairy Science·H BovenhuisJ A M van Arendonk

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Citations

Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rubén AgregánJosé M Lorenzo

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