Genetic and physical delineation of the region of the mouse deafness mutation shaker-2

Biochemical and Biophysical Research Communications
Y WakabayashiR Kominami

Abstract

A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a contig consisting of 21 BAC clones across an approximately 700-kb region of sh-2. This covers the entire nonrecombinant region of sh-2 and is therefore useful to facilitate the identification of genes in the sh-2 region.

Citations

Aug 31, 2001·ILAR Journal·Muriel T. DavissonJanan T. Eppig
Jul 21, 2000·DNA Sequence : the Journal of DNA Sequencing and Mapping·H D CampbellJ D Hoheisel
Oct 5, 2001·The American Journal of Pathology·R V LloydT B Friedman

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