Genetic background of acute coronary syndromes

European Journal of Internal Medicine
Jozefa DabekZbigniew Gasior

Abstract

Acute coronary syndromes (ACS) are one of the major causes of mortality nowadays. Although much is known about factors involved in atherogenesis and acute coronary events, there are still many cases in which a lack of classical risk factors, together with family history, suggests the presence of an unrevealed genetic predisposition and molecular mechanisms. This paper reviews genetic predisposition to ACS. It also indicates which genes are linked to the processes of destabilization and rupture of atherosclerotic plaque and thus may be potential targets for more effective prophylaxis and treatment.

References

Jan 14, 1999·Journal of Hypertension·F C Luft
Mar 7, 2000·Haemostasis·F AraújoL M Cunha-Ribeiro
May 16, 2000·Circulation Research·L W StantonR T White
May 15, 2002·Arteriosclerosis, Thrombosis, and Vascular Biology·Stephen B HarrapStanley T Anderson
May 31, 2003·Circulation Research·Gian Gastone Neri SerneriMario Chiavarelli
Sep 23, 2003·European Heart Journal·Shu YeChristopher N Martyn
Sep 23, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Shui Ping Zhao, Yi Fu Li
Oct 18, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Nejma AmezianeDominique de Prost
Jan 9, 2004·Japanese Heart Journal·Hitoshi NakajimaJunichiro Mizuguchi
Mar 25, 2004·European Heart Journal·Martin D TobinNilesh J Samani
May 19, 2004·Journal of Internal Medicine·E L GroveS D Kristensen
Dec 14, 2004·Human Genomics·Stephen Archacki, Qing Wang

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

ApoE Phenotypes

Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Related Papers

Asian Journal of Andrology
Elena Castro, Rosalind Eeles
Journal of the Science of Food and Agriculture
Faruq Golam, Zakaria H Prodhan
Folia medica Cracoviensia
Janusz FreyRoman Maria Herman
© 2022 Meta ULC. All rights reserved