Genetic changes and evolutionary analysis of canine circovirus.

Archives of Virology
Lin WangJunwei Ge

Abstract

Canine circovirus (canineCV) has been found to be associated with vasculitis, hemorrhage, hemorrhagic enteritis, and diarrhea of canines. CanineCV, like other circoviruses, may also be associated with lymphoid depletion and immunosuppression. This circovirus has been detected worldwide in different countries and species. Recombination and mutation events in the canineCV genome have been described, indicating that the virus is continuing to evolve. However, the origin, codon usage patterns, and host adaptation of canineCV remain to be studied. Here, the coding sequences of 93 canineCV sequences available in the GenBank database were used for analysis. The results showed that canineCV sequences could be classified into five genotypes, as confirmed by phylogenetic and principal component analysis (PCA). Maximum clade credibility (MCC) and maximum-likelihood (ML) trees suggested that canineCV originated from bat circovirus. G/T and A/C nucleotide biases were observed in ORF1 and ORF2, respectively, and a low codon usage bias (CUB) was found in canineCV using an effective number of codon (ENC) analysis. Correlation analysis, ENC plot analysis and neutrality plot analysis indicated that the codon usage pattern was mainly shaped by na...Continue Reading

References

Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·N Sueoka
May 5, 1982·Journal of Molecular Biology·J Kyte, R F Doolittle
Jan 27, 1999·Bioinformatics·D Posada, K A Crandall
Apr 26, 2001·Proceedings of the National Academy of Sciences of the United States of America·G MaraisL Duret
Nov 5, 2003·Bioinformatics·A CarboneF Képès
Sep 18, 2008·Biology Direct·Pere PuigbòSantiago Garcia-Vallve
Feb 13, 2010·Advances in Bioinformatics·Sameer HassanVanaja Kumar
Aug 21, 2010·BMC Evolutionary Biology·Emily H M WongLeo L M Poon
Mar 16, 2012·Virology Journal·Xin-sheng LiuYong-lu Wang
May 26, 2012·Journal of Virology·Amit KapoorW Ian Lipkin
Aug 15, 2012·Biological Reviews of the Cambridge Philosophical Society·Susanta K Behura, David W Severson
Feb 19, 2013·Transboundary and Emerging Diseases·T M L HuynhB K Park
May 1, 2013·Emerging Infectious Diseases·Linlin LiPatricia A Pesavento
Feb 22, 2014·Archives of Virology·Ye ChenChong Wang
Feb 6, 2016·Virology·Guendalina ZaccariaAlessio Lorusso
Jun 19, 2016·BMC Veterinary Research·Han-Siang HsuChao-Nan Lin
May 26, 2015·Virus Evolution·Darren P MartinBrejnev Muhire
Mar 1, 2017·The Veterinary Record·A AndersonS Unterer
May 4, 2018·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura
May 16, 2018·Scientific Reports·Chutchai PiewbangAlbert D M E Osterhaus
Jun 27, 2018·Virus Evolution·Marc A SuchardAndrew Rambaut
Nov 6, 2018·Virus Research·Wenchao SunNingyi Jin
Jan 22, 2019·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Urmil DaveSachin Kumar
Jun 4, 2019·Molecular Phylogenetics and Evolution·Wanting HeJiyong Zhou
Feb 10, 2020·Archives of Virology·Bornali DebSupriyo Chakraborty

❮ Previous
Next ❯

Software Mentioned

BEAST
LASERGENE
MaxChi
Modeltest
MEGA X
GENECONV
RDP4
FigTree
3Seq
CAI calculator

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.