Genetic characterisation and phylogenetic status of whipworms (Trichuris spp.) from captive non-human primates in China, determined by nuclear and mitochondrial sequencing

Parasites & Vectors
Yue XieGuangyou Yang

Abstract

Whipworms (Nematoda: Trichuridae), among the most common soil-transmitted helminths (STHs), can cause the socioeconomically important disease trichuriasis in various mammalian hosts including humans and non-human primates. For many years, Trichuris from non-human primates has been assigned to the same species as the one infecting humans Trichuris trichiura. More recently, several molecular reports challenged this assumption following recognition of a Trichuris species complex observed in humans and non-human primates. A refined concept for species limits within Trichuris contributes to an understanding of diversity and the potential (zoonotic) transmission among humans and non-human primates. In this study, we expanded previous investigations by exploring the diversity of Trichuris among eight primates including three Asian autochthonous species (i.e. Rhinopithecus roxellana, Rhinopithecus bieti and Nomascus leucogenys). Species-level identification, whether novel or assignable to known lineages of Trichuris, was based on analyses of nuclear internal transcribed spacers (ITS) and mitochondrial cytochrome c oxidase subunit 1 (cox1) genes. In total, seven genetically distinct subgroups of whipworms were determined to be present a...Continue Reading

References

Jan 1, 1989·Advances in Parasitology·D A Bundy, E S Cooper
Aug 23, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·L H TaylorM E Woolhouse
Aug 23, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·S CleavelandL H Taylor
Aug 24, 2006·Physiological and Biochemical Zoology : PBZ·Luis E CastanedaRoberto F Nespolo
Feb 23, 2007·International Journal for Parasitology·David E ElliottJoel V Weinstock
Sep 7, 2007·The New England Journal of Medicine·Peter J HotezLorenzo Savioli
May 27, 2009·Acta Tropica·C CutillasD C Guevara
Sep 14, 2010·Current Biology : CB·Karin Kiontke, David H A Fitch
Feb 22, 2012·Parasites & Vectors·Daniela LelesAdauto Araujo
Feb 24, 2012·Systematic Biology·Fredrik RonquistJohn P Huelsenbeck
Aug 1, 2012·Nature Methods·Diego DarribaDavid Posada
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Feb 18, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Eric P Hoberg, Daniel R Brooks
Jun 13, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Serena CavalleroFederica Berrilli
Sep 6, 2015·Parasitology Research·Rocío CallejónSteven A Nadler
Sep 25, 2015·Emerging Infectious Diseases·Bruno LeveckeJaco J Verweij
Jan 24, 2016·Parasites & Vectors·Mohamed B F HawashPeter Nejsum
Jun 18, 2016·Current Opinion in Genetics & Development·Sophie Tandonnet, Andre Pires-daSilva
Apr 11, 2017·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Rocío CallejónCristina Cutillas
Nov 9, 2017·Trends in Ecology & Evolution·Sören NylinNiklas Janz

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BETA
AM992981
AM992999

Methods Mentioned

BETA
PCR

Software Mentioned

jModeltest
Clustal X
MrBayes
PAUP
TreeviewX
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MEGA

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