Genetic characterisation of virulence genes associated with adherence, invasion and cytotoxicity in Campylobacter spp. isolated from commercial chickens and human clinical cases

The Onderstepoort Journal of Veterinary Research
Samantha Reddy, Oliver T Zishiri

Abstract

Virulence-associated genes have been recognised and detected in Campylobacter species. The majority of them have been proven to be associated with pathogenicity. This study aimed to detect the presence of virulence genes associated with pathogenicity and responsible for invasion, expression of adherence, colonisation and production of the cytolethal distending toxin (cdt) in Campylobacter jejuni and Campylobacter coli. Commercial chicken faecal samples were randomly sampled from chicken farms within the Durban metropolitan area in South Africa. Furthermore, human clinical Campylobacter spp. isolates were randomly sampled from a private pathology laboratory in South Africa. Out of a total of 100 chicken faecal samples, 78% (n = 78) were positive for Campylobacter growth on modified charcoal cefoperazone deoxycholate and from the random laboratory collection of 100 human clinical isolates, 83% (n = 83) demonstrated positive Campylobacter spp. growth following culturing methods. These samples were screened for the presence of the following virulence genes: cadF, hipO, asp, ciaB, dnaJ, pldA, cdtA, cdtB and cdtC. As expected, the cadF gene was present in 100% of poultry (n = 78) and human clinical isolates (n = 83). Campylobacter je...Continue Reading

References

May 4, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Morton N Swartz
Sep 26, 2007·Journal of Medical Microbiology·Aisha Al AmriGiuseppe A Botta
May 21, 2008·Cellular Microbiology·Zhongming GeJames G Fox
Jul 21, 2009·Journal of Bacteriology·Alejandro Caro-QuinteroKonstantinos T Konstantinidis
Aug 14, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·H NielsenH C Schønheyder
Jul 1, 2011·Veterinary Research·David HermansFrank Pasmans
Sep 17, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Benjamin FeodoroffHilpi Rautelin
Mar 1, 2012·Frontiers in Microbiology·Ioanna MarinouStylianos Chatzipanagiotou
Mar 17, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mussaret B ZaidiJuan J Calva
Aug 25, 2012·Frontiers in Cellular and Infection Microbiology·Tadhg O Cróinín, Steffen Backert
Jul 23, 2013·Journal of Microbiological Methods·Eduardo N TaboadaCatherine D Carrillo
Nov 30, 2013·International Journal of Environmental Research and Public Health·Sharon V R EppsDavid J Nisbet
Feb 12, 2014·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Aline Feola de CarvalhoEliana Scarcelli
Jun 21, 2014·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·B B FonsecaM E Beletti
Jul 16, 2014·Nature Reviews. Neurology·Bianca van den BergPieter A van Doorn
Nov 20, 2014·The Open Microbiology Journal·Aneesa Noormohamed, Mohamed K Fakhr
Jun 13, 2015·Clinical Microbiology Reviews·Nadeem O KaakoushSi Ming Man
Jun 7, 2017·The Onderstepoort Journal of Veterinary Research·Samantha Reddy, Oliver T Zishiri

❮ Previous
Next ❯

Citations

Mar 20, 2021·Microbiology Resource Announcements·Jaya Lakshmi SsBalaji Veeraraghavan
Nov 14, 2020·Applied Microbiology and Biotechnology·Vanessa KrelingAndreas Hensel
Aug 4, 2021·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Manel GharbiAbderrazek Maaroufi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Campylobacteriosis

Campylobacteriosis is caused by the bacteria Campylobacter jejuni and is a common cause of gastroenteritis in humans. Discover the latest research on Campylobacteriosis here.

Campylobacteriosis (ASM)

Campylobacteriosis is caused by the bacteria Campylobacter jejuni and is a common cause of gastroenteritis in humans. Discover the latest research on Campylobacteriosis here.