PMID: 2498876May 1, 1989Paper

Genetic characterization of clones of the bacterium Listeria monocytogenes causing epidemic disease

Proceedings of the National Academy of Sciences of the United States of America
J C PiffarettiJ Rocourt

Abstract

One hundred and seventy-five isolates of the pathogenic bacterium Listeria monocytogenes recovered from human clinical (blood and cerebrospinal fluid), animal, and environmental sources in Europe, North America, and elsewhere were analyzed electrophoretically for allelic variation at 16 genetic loci encoding metabolic enzymes. Forty-five distinctive allele profiles (electrophoretic types, ETs) were distinguished, among which mean genetic diversity per locus (H) was 0.424. Cluster analysis of a matrix of genetic distances between paired ETs revealed two primary phylogenetic divisions of the species separated at a distance of 0.54. ETs in division I were presented by strains of serotypes 4b, 1/2b, and 4a, whereas strains of ETs in division II were of serotypes 1/2a and 1/2c. Human and animal isolates did not represent distinctive subsets of ETs. The occurrence of linkage disequilibrium between enzyme loci and the widespread distribution of certain ETs indicate that the genetic structure of L. monocytogenes is clonal. One clone, marked by ET1, caused major epidemics of human disease in western Switzerland in the period 1983-1987 and in Los Angeles County, California, in 1985, both of which were attributed to contamination of soft ...Continue Reading

References

Apr 1, 1988·The Journal of Experimental Medicine·D A PortnoyD J Hinrichs
Oct 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·J M MusserR K Selander
Jul 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·D A CaugantR K Selander
Dec 1, 1986·Journal of Medical Microbiology·J McLauchlinA G Taylor
Sep 29, 1988·The New England Journal of Medicine·M J LinnanR Weaver
Jul 1, 1987·Microbial Pathogenesis·R K SelanderT S Whittam
Feb 14, 1985·The New England Journal of Medicine·D W FlemingA L Reingold
Jul 1, 1985·Zentralblatt Für Bakteriologie, Mikrobiologie, Und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology·J RocourtA G Taylor
Sep 1, 1983·Journal of General Microbiology·H OchmanR K Selander
Jan 27, 1983·The New England Journal of Medicine·W F SchlechC V Broome

❮ Previous
Next ❯

Citations

Mar 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J McLauchlin
Mar 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D NoceraJ Bille
Nov 10, 1990·Lancet·D Jones
Jul 1, 1992·International Journal of Food Microbiology·H Hof, J Rocourt
Jul 1, 1992·International Journal of Food Microbiology·J KolstadL M Rørvik
Jan 1, 1992·International Journal of Food Microbiology·B Nørrung
Oct 1, 1995·International Journal of Food Microbiology·F M Wu, P M Muriana
Jan 1, 1996·International Journal of Food Microbiology·S M AveryS Buncic
Aug 1, 1996·International Journal of Food Microbiology·T NesbakkenD A Caugant
Aug 1, 1996·International Journal of Food Microbiology·E BannermanJ Bille
Jan 1, 1996·Meat Science·T Nesbakken, E Skjerve
Feb 1, 1995·Research in Microbiology·T Gormon, L Phan-Thanh
Jan 13, 2001·International Journal of Food Microbiology·J RocourtA Reilly
Oct 7, 1998·International Journal of Food Microbiology·A KerouantonB Picard
Jan 30, 2003·Veterinary Microbiology·Monica K BoruckiDouglas R Call
Jan 1, 1997·The Veterinary Journal·J C Low, W Donachie
Jun 22, 2001·Microbes and Infection·J A Vázquez-BolandW Goebel
Nov 25, 2011·Proceedings of the National Academy of Sciences of the United States of America·Pascale Cossart
Oct 16, 2012·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Atin R DattaMarianne Solomotis
Oct 14, 2008·Foodborne Pathogens and Disease·Vishal Singh PariharWilhelm Tham
Nov 19, 2008·Foodborne Pathogens and Disease·Sara R Milillo, Martin Wiedmann
Nov 17, 2009·Foodborne Pathogens and Disease·Henk C den BakkerMartin Wiedmann
Jan 6, 2001·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·D S BlancUNKNOWN Swiss MRSA Group
May 8, 1998·Microbiology and Immunology·K MoriishiS Inoue
Mar 5, 2013·Applied and Environmental Microbiology·Paulo Ricardo Dell'Armelina RochaCristina Casalone
Jul 27, 2010·Applied and Environmental Microbiology·Henk C den BakkerMartin Wiedmann
Jan 16, 2007·Applied and Environmental Microbiology·Dmitriy V VolokhovAnthony D Hitchins

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.