PMID: 8604558Nov 1, 1995Paper

Genetic characterization of mycobacteria from South American wild seals

Veterinary Microbiology
M I RomanoAngel Cataldi

Abstract

Tuberculosis has been recently diagnosed in four wild seals found stranded in the Atlantic coast of Argentina. By bacteriological studies and IS6110 hybridization, these isolates were characterized as belonging to the Mycobacterium tuberculosis complex. A genetic characterization using RFLP (Restriction fragment length polymorphism) and a species-specific probe of M. tuberculosis, called mtp40, showed hybridization with this probe on a single band. A similar band was also found in M. tuberculosis H37Rv. This showed a relationship between M. tuberculosis and the wild seal isolates. However these would also seem to belong to a different genetic group in the M. tuberculosis complex, since they do not grow on glycerol-egg containing medium (Lowenstein-Jensen) as typical M. tuberculosis strains usually do. Repeated sequences pMBA2, pTNB12, DR and IS6110 were used as probes to evaluate the epidemiological relationships between the 4 cases of tuberculosis. A low degree of polymorphism was observed, that suggested that these isolates were epidemiologically related.

References

Sep 15, 1992·FEMS Microbiology Letters·T J DoranA J Radford
May 1, 1995·Research in Microbiology·F BigiA Cataldi
Mar 1, 1993·Australian Veterinary Journal·D V CousinsN Gales
Feb 1, 1993·Research in Microbiology·J T Crawford

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Citations

Mar 24, 2004·Veterinary Microbiology·R AlfonsoM A Patarroyo
Jul 1, 1998·Veterinary Microbiology·J C FisanottiM I Romano
Oct 6, 1999·Veterinary Microbiology·A AlitoA Cataldi
Jun 1, 1997·Research in Microbiology·J C FisanottiA Cataldi
Jun 12, 2003·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Niyaz AhmedSeyed E Hasnain
Mar 7, 2001·Journal of Clinical Microbiology·K CaimiA Cataldi
Jan 19, 2013·The Onderstepoort Journal of Veterinary Research·Erasto V MbugiMecky I Matee
Apr 14, 2015·Future Microbiology·Md Masudur RahmanHossam M Ashour
Jun 28, 2005·FEMS Microbiology Letters·Fabiana BigiMaria I Romano
May 29, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·F BigiA A Cataldi
Sep 18, 2003·International Journal of Systematic and Evolutionary Microbiology·Debby V CousinsAmelia Bernardelli
Oct 12, 1999·Microbiology·M J ZumárragaM I Romano
Jun 12, 1999·Journal of Clinical Microbiology·J G RodríguezA Cataldi

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