Genetic Conservation of Phosphine Resistance in the Rice Weevil Sitophilus oryzae (L.)

The Journal of Heredity
Tam T NguyenPaul R Ebert

Abstract

High levels of resistance to phosphine in the rice weevil Sitophilus oryzae have been detected in Asian countries including China and Vietnam, however there is limited knowledge of the genetic mechanism of resistance in these strains. We find that the genetic basis of strong phosphine resistance is conserved between strains of S. oryzae from China, Vietnam, and Australia. Each of 4 strongly resistant strains has an identical amino acid variant in the encoded dihydrolipoamide dehydrogenase (DLD) enzyme that was previously identified as a resistance factor in Rhyzopertha dominica and Tribolium castaneum. The unique amino acid substitution, Asparagine > Threonine (N505T) of all strongly resistant S. oryzae corresponds to the position of an Asparagine > Histidine variant (N506H) that was previously reported in strongly resistant R. dominica. Progeny (F16 and F18) from 2 independent crosses showed absolute linkage of N505T to the strong resistance phenotype, indicating that if N505T was not itself the resistance variant that it resided within 1 or 2 genes of the resistance factor. Non-complementation between the strains confirmed the shared genetic basis of strong resistance, which was supported by the very similar level of resistan...Continue Reading

References

Mar 21, 2002·Insect Molecular Biology·D I SchlipaliusP R Ebert
Sep 10, 2002·Journal of Economic Entomology·Patrick J CollinsHervoika Pavic
Jun 29, 2007·Pest Management Science·Marco Aurélio G PimentelRaul Narciso C Guedes
Mar 26, 2008·Nature·UNKNOWN Tribolium Genome Sequencing ConsortiumGregor Bucher
Nov 10, 2012·Science·David I SchlipaliusPaul R Ebert
Jan 1, 2013·The Journal of Heredity·C Scott Baker

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Citations

Dec 3, 2020·Insects·Darka HamelAnita Liška

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