PMID: 3113931Jan 1, 1987Paper

Genetic considerations in childhood epilepsy

Epilepsia
T D Bird

Abstract

This report reviews various lines of evidence demonstrating important genetic influences in the epilepsies, with special emphasis on childhood epilepsy. Five pertinent topics are discussed: (a) examples of dominant, recessive, and X-linked single-gene disorders known to be associated with epilepsy, (b) examples of gross chromosomal aberrations associated with epilepsy, (c) discussion of multifactorial and polygenic inheritance and issues of genetic heterogeneity with specific reference to idiopathic generalized epilepsy, febrile seizures, and infantile spasms, (d) brief review of experimental clues to possible pathogenetic mechanisms underlying genetic forms of epilepsy, and (e) an overview of strategies for applying genetic linkage analysis to hereditary epileptic disorders.

References

Dec 22, 1978·Journal of Neurology·E BoltshauserT Deonna
Nov 1, 1979·Archives of Dermatology·J E Morgan, F Wolfort
Jul 31, 1986·The New England Journal of Medicine·S F BerkovicL S Wolfe
Apr 4, 1986·Science·M S Brown, J L Goldstein
Mar 1, 1985·Epilepsia·T N Seyfried, G H Glaser
Nov 1, 1985·Epilepsia·J L HainesV E Anderson
Mar 1, 1973·Epilepsia·H DooseE Völzke
Jun 1, 1968·Epilepsia·H DooseE Völzke
Nov 1, 1984·Annals of Neurology·A G Engel
Aug 9, 1984·The New England Journal of Medicine·D J Prockop, K I Kivirikko
Jun 1, 1984·Journal of Neurochemistry·S T Palayoor, T N Seyfried
Jun 1, 1983·Muscle & Nerve·A D RosesD B Carter
Nov 17, 1983·Nature·J F GusellaA Y Sakaguchi
Jan 1, 1983·Annual Review of Medicine·D G Hirtz, K B Nelson
Mar 1, 1984·Neurology·A V Delgado-Escueta, F Enrile-Bacsal
Jul 1, 1984·American Journal of Medical Genetics·J ZonanaB Strimling
Dec 1, 1983·American Journal of Medical Genetics·R E Kaplan, D J Lacey
Jun 1, 1980·Neurochemical Research·N M van GelderJ D Metrakos
Oct 1, 1980·Journal of the American Podiatry Association·M E Julsrud
Jan 1, 1980·Archives of Neurology·R E Pettit, G M Fenichel
Nov 1, 1961·Neurology·S A SCHNECK, K N VON KAULLA

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Citations

Nov 27, 1998·Pediatric Neurology·W O TatumP Genton
May 24, 2003·Seizure : the Journal of the British Epilepsy Association·Sema SaltikAysin Dervant
May 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·T SugawaraK Yamakawa
Jan 1, 1992·Acta Neurologica Scandinavica. Supplementum·R CangerC A Tassinari
Oct 29, 2002·Annals of Neurology·Junko NakayamaLouis J Ptácek
Aug 5, 2006·Epilepsy Research·Junko Nakayama, Tadao Arinami
Jan 1, 1993·Epilepsia·L J Treiman
Apr 18, 2018·Expert Reviews in Molecular Medicine·Hao DengZhi Song
Apr 13, 1996·The Veterinary Record·S J Hall, M E Wallace

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