DOI: 10.1101/19008342Oct 18, 2019Paper

Genetic determinants of trehalose utilization are not associated with severe Clostridium difficile infection

MedRxiv : the Preprint Server for Health Sciences
Katie SaundEvan S Snitkin


In a case-control study of patients with C. difficile infection we found no statistically significant association between the presence of trehalose utilization variants in infecting C. difficile strains and development of severe infection. These results do not support trehalose utilization conferring enhanced virulence in the context of human C. difficile infections.

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