Jul 1, 1976

Genetic differences in lymphoid tissue reactivity during liver regeneration in mice of different lines

Biulleten' eksperimental'noĭ biologii i meditsiny
A G BabaevaS S Gambarov

Abstract

The transfer of lymphocytes together with sheep erythrocytes from partially hepatectomized mice to syngenous lethally irradiated mice (CAB and C57BL) increased the number of antibody forming cells in the recipient's spleen. The lymphocytes of CBA mice acquired this ability much earlier after the operation (in 4 hours) than those of the C57BL mice (in 17 hours). After the transfer of lymphocytes in the semisyngenous system there was a decrease of antibody forming cells during subsequent recipient's immunization with sheep erythrocytes; this was the result of the graft versus host reaction. The latter reaction was less marked in the operated than in control mice. These changes also occurred earlier after the operation in the CBA than in C57BL mice.

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Mentioned in this Paper

Spleen
Hybridization, Intraspecies
Lymphoid Cells
Graft Vs Host Reaction
Antibody Formation
Antibody-Secreting Cells
Transplantation, Homologous
Lymphocyte Transfusion
Liver Regeneration

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