Genetic diversity among human immunodeficiency virus-1 non-B subtypes in viral load and drug resistance assays

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
M PeetersE Delaporte

Abstract

The tremendous diversity of human immunodeficiency virus (HIV)-1 strains circulating worldwide has an important impact on almost all aspects of the management of this infection, from the identification of infected persons, through treatment efficacy and monitoring, and prevention strategies such as vaccine design. The areas where HIV-1 genetic diversity is highest are those where the majority of patients in need of treatment and biological monitoring live. With increased access to treatment in these areas, it is expected that the demand for monitoring tools such as viral load assays and resistance tests will also increase, and their reliability will be critical. Regular updates of these assays during the last two decades have aimed at improving their performances in different ways that include their reliability with different HIV-1 strains. We here review to what extent HIV-1 genetic diversity still limits or not the use of currently available viral load and resistance tests.

References

Sep 30, 1995·Lancet·I Loussert-AjakaS Saragosti
Feb 24, 1999·AIDS Research and Human Retroviruses·B ParekhR Respess
Apr 15, 2000·Science·D L RobertsonB Korber
Feb 28, 2002·AIDS Research and Human Retroviruses·Rob SchuurmanUNKNOWN ENVA Working Group
Feb 25, 2003·AIDS Research and Human Retroviruses·Herve FleuryUNKNOWN Agence Nationale de Recherche sur le SIDA AC11 Laboratory Network
Apr 2, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A HolguínV Soriano
Apr 19, 2003·Journal of Clinical Microbiology·Robert M GrantDean L Winslow
Jun 7, 2003·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jean-Christophe PlantierFrançois Simon
Sep 23, 2003·Journal of Virological Methods·Marie GueudinFrançois Simon
Apr 28, 2004·Journal of Virological Methods·Bart MaesKristel Van Laethem
Jul 13, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Iain D TattJohn V Parry
Mar 23, 2005·Nature Methods·Chanjuan ShiJames R Eshleman
Sep 8, 2005·Journal of Clinical Microbiology·C Y W TongI L Chrystie
Apr 20, 2006·Journal of Medical Virology·Francine E McCutchan
May 27, 2006·Science·Brandon F KeeleBeatrice H Hahn
Aug 22, 2006·The Journal of Infectious Diseases·Mark Holodniy
Feb 3, 2007·Current HIV Research·Isolde F ButlerCristian Apetrei
May 11, 2007·Expert Review of Molecular Diagnostics·Miriam WittekAnnemarie Berger
Aug 9, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Vladimir NovitskyM Essex
Jan 4, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Craig Corcoran, Diana Hardie
Jun 11, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Agnès Gautheret-DejeanJean-Christophe Plantier
Apr 14, 2010·AIDS·Aurélia VessièreJean-Christophe Plantier
Apr 17, 2010·AIDS·William H WheelerUNKNOWN Variant, Atypical, and Resistant HIV Surveillance Group

❮ Previous
Next ❯

Citations

Apr 1, 2011·AIDS Research and Human Retroviruses·Jutarat PraparattanapanKhuanchai Supparatpinyo
Mar 16, 2012·AIDS Research and Human Retroviruses·Maria Mercedes SantoroCarlo Federico Perno
Feb 2, 2012·The Journal of Infectious Diseases·Eric DelwartUNKNOWN NHLBI-REDS-II Study Group
Dec 18, 2012·Journal of Clinical Microbiology·Moussa ThiamCoumba Toure-Kane
Apr 4, 2012·PloS One·Matthieu JungMartine Peeters
May 1, 2011·Expert Opinion on Medical Diagnostics·François RouetEric Nerrienet
Feb 24, 2016·Nigerian Medical Journal : Journal of the Nigeria Medical Association·Mohammad-Ali JenabianLaurent Bélec
Oct 16, 2013·Journal of Medical Virology·Augustin Mouinga-OndéméFrançois Rouet
Sep 26, 2012·Current Opinion in Virology·R J LessellsT de Oliveira
Mar 26, 2014·The International Journal of Biochemistry & Cell Biology·Nianxi ZhaoYouli Zu
Dec 26, 2012·Journal of Virological Methods·Moussa ThiamCoumba Toure-Kane
Jun 18, 2016·PloS One·Bhavna HoraUNKNOWN REDS-III and EQAPOL programs
Nov 9, 2011·The Biochemical Journal·Puppala MuthennaG Bhanuprakash Reddy
Mar 15, 2015·The Open AIDS Journal·Linda Chapdeleine Mekue MouafoLaurent Bélec
Oct 25, 2013·PloS One·Charitra N GramaGeereddy Bhanuprakash Reddy
Oct 11, 2017·The Pediatric Infectious Disease Journal·Patricia Rojas SánchezUNKNOWN Madrid Cohort of HIV-1 Infected Children and Adolescents Integrated in the Pediatric Branch of the Spanish National AIDS Net
Jan 1, 2017·Voprosy virusologii·E V KazennovaM R Bobkova
May 6, 2016·Journal of Enzyme Inhibition and Medicinal Chemistry·Kapil K PatilRajesh N Gacche
Jul 4, 2018·Future Virology·Juan Á Patiño-Galindo, Fernando González-Candelas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.