Genetic diversity of the Thao people of Taiwan using Y-chromosome, mitochondrial DNA and HLA gene systems

BMC Evolutionary Biology
Jean A TrejautMarie Lin

Abstract

Despite attempts in retracing the history of the Thao people in Taiwan using folktales, linguistics, physical anthropology, and ethnic studies, their history remains incomplete. The heritage of Thao has been associated with the Pazeh Western plains peoples and several other mountain peoples of Taiwan. In the last 400 years, their culture and genetic profile have been reshaped by East Asian migrants. They were displaced by the Japanese and the construction of a dam and almost faced extinction. In this paper, genetic information from mitochondrial DNA (mtDNA), Histoleucocyte antigens (HLA), and the non-recombining Y chromosome of 30 Thao individuals are compared to 836 other Taiwan Mountain and Plains Aborigines (TwrIP & TwPp), 384 Non-Aboriginal Taiwanese (non-TwA) and 149 Continental East Asians. The phylogeographic analyses of mtDNA haplogroups F4b and B4b1a2 indicated gene flow between Thao, Bunun, and Tsou, and suggested a common ancestry from 10,000 to 3000 years ago. A claim of close contact with the heavily Sinicized Pazeh of the plains was not rejected and suggests that the plains and mountain peoples most likely shared the same Austronesian agriculturist gene pool in the Neolithic. Having been moving repeatedly since th...Continue Reading

References

Mar 1, 1972·Theoretical Population Biology·W J Ewens
Mar 21, 1998·Nature Genetics·T F BergströmU Gyllensten
Aug 5, 2000·American Journal of Human Genetics·J SaillardS Nørby
Mar 1, 2003·Nature Genetics·L Luca Cavalli-Sforza, Marcus W Feldman
May 20, 2003·Tissue Antigens·D MiddletonR Komerofsky
Sep 26, 2003·European Journal of Human Genetics : EJHG·Nicole Maca-MeyerJosé M Larruga
Dec 24, 2003·American Journal of Human Genetics·Lev A ZhivotovskyLuba Kalaydjieva
Sep 24, 2005·Science·Henry Harpending, Vinayak Eswaran
Nov 13, 2007·BMC Evolutionary Biology·Alexei J Drummond, Andrew Rambaut
Mar 25, 2008·Molecular Biology and Evolution·Pedro SoaresMartin B Richards
May 17, 2008·BMC Evolutionary Biology·Hui LiLi Jin
Oct 15, 2008·Human Mutation·Mannis van Oven, Manfred Kayser
Jun 9, 2009·American Journal of Human Genetics·Pedro SoaresMartin B Richards
Sep 17, 2009·Molecular Biology and Evolution·Kristina A TabbadaMaria Corazon A De Ungria
Sep 30, 2010·European Journal of Human Genetics : EJHG·Frederick DelfinMaria Corazon A De Ungria
Apr 21, 2011·European Journal of Human Genetics : EJHG·Shi YanUNKNOWN Genographic Consortium
Jan 25, 2013·Journal of Human Genetics·Meryanne K TumonggorMurray P Cox
Mar 13, 2014·American Journal of Human Genetics·Albert Min-Shan KoYing-Chin Ko
Jan 20, 2016·Human Genetics·Pedro A SoaresMartin B Richards

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Citations

Aug 28, 2020·American Journal of Human Biology : the Official Journal of the Human Biology Council·Jin SunHui Li

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Datasets Mentioned

BETA
MH177784-
MH177821

Methods Mentioned

BETA
MDS
genotyping
PCR
electrophoresis

Software Mentioned

Genotyper
SPSS
Beast
Arlequin
TwMix
Network
Phylotree

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