Genetic drift in clines which are maintained by migration and natural selection.

Genetics
J Felsenstein

Abstract

Genetic drift will cause a migration-selection cline to wobble about its expected position. A rough linear approximation is developed, valid when local populations are large. This is used to calculate effects of genetic drift on clines in a stepping-stone model with abrupt and with gradual changes of selection coefficients at a single haploid locus. Among the quantities calculated are measures of slope, standardized variation of gene frequencies around their expected values, and correlation among neighboring populations with respect to deviations from the expected gene frequencies. These quantities appear to be primarily functions of Ns and Nm for a given pattern of selection. Computer simulation gives rough confirmation of these results. Standardized variances of gene frequencies and correlation of neighbors differ along the cline in the case of smooth changes in selection. In no case is pathological behavior of gene frequency deviations found near the boundaries of selective regions. Local behavior of gene frequences of nearby colonies is approximately predicted by a simple adaptation of the stepping-stone theory of Kimura and Weiss. Approximate measures of the lateral variation of the midpoint of a cline and the probability ...Continue Reading

Citations

Jan 13, 2006·Journal of Evolutionary Biology·M Alleaume-BenhariraO Ronce
May 11, 2018·Proceedings. Biological Sciences·James S SantangeloRob W Ness
May 29, 2018·Evolution; International Journal of Organic Evolution·John A HvalaBret A Payseur
Jan 15, 2005·Theoretical Population Biology·Michael M Desai, David R Nelson
Sep 17, 2019·Trends in Ecology & Evolution·Nathan J WhiteIsobel Eyres
May 6, 2016·Molecular Ecology·Alisa SedghifarPeter Ralph
Jun 28, 2011·Genetics·Jitka Polechová, Nick Barton
Apr 6, 2011·Evolution; International Journal of Organic Evolution·Petra DufkováJaroslav Piálek

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