Genetic evolution of swine influenza A (H3N2) viruses in China from 1970 to 2006

Journal of Clinical Microbiology
Hai YuGuang-Zhi Tong

Abstract

Pigs are susceptible to both human and avian influenza viruses and have been proposed to be intermediate hosts, or mixing vessels, for the generation of pandemic influenza viruses through reassortment or adaptation to the mammalian host. In this study, we summarize and report for the first time the coexistence of wholly human-like H3N2 viruses, double-reassortant H3N2 viruses, and triple-reassortant H3N2 viruses in pigs in China by analyzing the eight genes of swine influenza A (H3N2) viruses found in China from 1970 to 2006. In 1970, the first wholly human-like H3N2 (Hong Kong/68-like) viruses were isolated from pigs in Taiwan, and then in the next years Victoria/75-like, Sydney/97-like, New York/99-like, and Moscow/99-like swine H3N2 viruses were regularly isolated in China. In the 1980s, two triple-reassortant viruses were isolated from pigs. Recently, the double-reassortant viruses containing genes from the human (HA and NA) and avian (PB2, PB1, PA, NP, M, and NS) lineages and the triple-reassortant viruses containing genes from the human (HA and NA), classical swine (NP), and avian (PB2, PB1, PA, M, and NS) lineages emerged in pigs in China. The coexistence of wholly human-like and reassortant viruses provides further evid...Continue Reading

References

Jun 24, 1977·Science·K F ShortridgeC H Campbell
Oct 9, 1982·Lancet·K F Shortridge, C H Stuart-Harris
Mar 1, 1995·The Journal of General Virology·K NeromeM Ishida
Dec 1, 1995·The Journal of Veterinary Medical Science·K KatsudaH Goto
Aug 1, 1997·The Journal of Infectious Diseases·I T Schulze
May 9, 2000·Veterinary Microbiology·I H Brown
Aug 23, 2000·Journal of Virology·R J WebbyR G Webster
Nov 23, 2000·Journal of Virology·Y SuzukiY Kawaoka
Sep 29, 2001·Journal of Applied Microbiology·C W Potter
Apr 11, 2003·Vaccine·Ron A M FouchierIan H Brown
May 8, 2003·Journal of Clinical Microbiology·Gabriele A LandoltChristopher W Olsen
Dec 8, 2005·Journal of Clinical Microbiology·X Sherry ChiSheau-Mei Cheng
Mar 10, 2007·Biochemical and Biophysical Research Communications·Hai YuGuang-Zhi Tong
Mar 17, 2007·Nature Reviews. Immunology·Kanta Subbarao, Tomy Joseph
Jun 1, 2006·The Veterinary Quarterly·H KothalawalaE Gruys

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Citations

May 14, 2010·Animal Health Research Reviews·Wenjun Ma, Jürgen A Richt
Nov 26, 2009·Virology Journal·Adrian J GibbsJean C Downie
Jul 1, 2010·Emerging Infectious Diseases·Yuhai BiJinhua Liu
Jan 16, 2014·Indian Journal of Microbiology·Weili KongJuan Pu
Aug 25, 2010·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Lu LuWenjun Liu
May 23, 2009·Biochemical and Biophysical Research Communications·Hai YuGuang-Zhi Tong
Jun 3, 2009·Zoonoses and Public Health·W MaJ A Richt
Nov 12, 2009·Influenza and Other Respiratory Viruses·Varough DeydeLarisa Gubareva
Sep 22, 2009·Influenza and Other Respiratory Viruses·Christy Brockwell-StaatsRichard J Webby
May 21, 2009·Influenza and Other Respiratory Viruses·Nobuhiro TakemaeTakehiko Saito
Dec 17, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Lei SunWenjun Liu
Jun 23, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·J S Malik PeirisYi Guan
Sep 5, 2012·Journal of Virological Methods·Andrzej KowalczykThomas Bruun Rasmussen
Dec 24, 2013·Veterinary Pathology·B H Janke
Apr 7, 2016·Journal of Veterinary Science·Feng WenGuang-Zhi Tong
May 27, 2011·Nature·Dhanasekaran VijaykrishnaJ S Malik Peiris

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