Genetic influences in common respiratory disorders

Critical Care Nursing Clinics of North America
M Linda Workman, Chris Winkelman

Abstract

Respiratory disorders are common problems for adults and children in North America and generally represent the outcome of gene-environment interactions. Some problems are considered genetic in origin, such as cystic fibrosis, and others are considered environmental in origin, such as respiratory infections. Emerging information indicates that even genetic-based disorders are influenced by the environment and that environmental-based disorders are modified by personal genetic factors in individual physiologic responses. An understanding of an individual's personal risk factors for disease or health problem development can allow health care professionals to tailor health promotion strategies and treatment plans with appropriate environmental manipulation. This article explores the genetic influences that may affect the individual's physiologic responses and the consequences of environmental stimuli.

References

Feb 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·G J DarlingtonM Smith
May 1, 1993·The American Review of Respiratory Disease·J FarjanelG Offenstadt
May 2, 1997·Science·E J Strauss, S Falkow
Dec 11, 1999·Cancer Investigation·M R SpitzX Wu
Jul 7, 2000·American Journal of Human Genetics·C M GreenwoodK Morgan
Sep 7, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L LaforestK Husgafvel-Pursiainen
Sep 18, 2002·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Chikako KiyoharaJulian M Hopkin
Dec 28, 2002·American Journal of Medical Genetics. Part a·Lucas L KulczyckiJoseph A Bellanti
Feb 25, 2003·Critical Care Nursing Clinics of North America·M Linda Workman
Sep 1, 1963·The Journal of Pediatrics·T S THOMAIDIS, J B AREY
Dec 25, 1964·Science·F KUEPPERSA G BEARN
Aug 24, 2004·Oncogene·Xifeng WuDavid C Christiani
Aug 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·William PaoHarold Varmus
Aug 17, 2005·Proceedings of the National Academy of Sciences of the United States of America·Suneil MalikErwin Schurr
Oct 26, 2005·Nature Medicine·Dianhua JiangPaul W Noble
Aug 17, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Torsten T BauerEckhard E Müller
Jul 3, 2007·Nursing·Janelle Gardner
Apr 22, 2008·Critical Care Nursing Clinics of North America·Chris Winkelman

❮ Previous
Next ❯

Citations

Sep 28, 2013·FEBS Letters·Ni ZhangLijun Xu
Sep 30, 2015·In Vitro Cellular & Developmental Biology. Animal·Zhize ChenZhongyuan Xia

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine
Umesh T SankpalRiyaz Basha
American Journal of Respiratory Cell and Molecular Biology
Courtney A Granville, Phillip A Dennis
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Matthew Meyerson, David Carbone
© 2022 Meta ULC. All rights reserved