Genetic influences on the association between personality risk factors and alcohol use and abuse

Journal of Abnormal Psychology
Brian S MustanskiRichard J Rose

Abstract

The authors assessed the association of 2 personality dimensions with use and abuse of alcohol in 1,320 twin pairs concordantly reporting nonabstinence at age 18.5 years. The 2 alcohol outcomes differentially relate to the 2 personality dimensions: Alcohol-related problems correlate more highly with social deviance than with excitement seeking (ES), and alcohol consumption correlates more highly with ES than with social deviance. Biometric models fit to the data identified similar patterns in genetic covariance, although differences were more evident in genetic correlations between social deviance and alcohol outcomes than in those for ES. Results suggest that genetic influences underlie the association of personality with alcohol use and subsequent problems and illustrate the utility of informative twin analyses in exploring links between genes, personality, and behavior disorder.

References

Dec 1, 1979·Psychiatry Research·M Zuckerman, M Neeb
Apr 24, 1987·Science·C R Cloninger
Jan 1, 1989·Journal of Studies on Alcohol·H R White, E W Labouvie
Apr 1, 1988·Journal of Consulting and Clinical Psychology·P E Nathan
Aug 1, 1973·Journal of Abnormal Psychology·R G LoperH Hoffmann
Jul 1, 1995·Behavior Genetics·J R KoopmansL J van Doornen
May 1, 1997·Alcoholism, Clinical and Experimental Research·M McGueW G Iacono
May 4, 1999·Journal of Studies on Alcohol. Supplement·R J RoseR J Viken
Mar 31, 2000·Journal of Abnormal Psychology·P R FinnN Turcotte
Aug 3, 2000·Alcoholism, Clinical and Experimental Research·A N JustusJ E Steinmetz
Nov 9, 2000·Addiction·D M Fergusson, L J Horwood
Nov 9, 2001·Behavior Genetics·T J Bouchard, J C Loehlin
May 1, 1997·Alcoholism, Clinical and Experimental Research·Matt McGueWilliam G Lacono

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Citations

Dec 25, 2010·Journal of Abnormal Child Psychology·Natalie Castellanos-Ryan, Patricia J Conrod
Dec 15, 2005·Journal of Abnormal Psychology·Lee Anna Clark
Dec 15, 2005·Journal of Abnormal Psychology·Robert F KruegerWilliam G Iacono
Apr 15, 2010·Journal of Addictive Diseases·Ian R GizerKirk C Wilhelmsen
Jun 2, 2007·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Richard J VikenRichard J Rose
May 22, 2009·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Tellervo KorhonenJaakko Kaprio
Apr 9, 2013·Clinical Psychology Review·Kaidy Stautz, Andrew Cooper
Aug 30, 2008·Substance Use & Misuse·Cecilia Peñacoba PuenteAlmudena López López
Sep 6, 2011·Clinical Psychology Review·Serena BezdjianCatherine Tuvblad
Apr 16, 2004·Alcoholism, Clinical and Experimental Research·Caroline BrunelleRobert O Pihl
Dec 15, 2010·Alcoholism, Clinical and Experimental Research·Clare J MackieThalia C Eley
Apr 9, 2010·Alcoholism, Clinical and Experimental Research·George FeinPeter Finn
Feb 7, 2012·Behavior Therapy·Tamara Goldman Sher
Dec 14, 2005·Addictive Behaviors·James B Hittner, Rhonda Swickert
Apr 17, 2013·Addictive Behaviors·Rachel L GunnSuzanne Spinola
Jan 30, 2007·Journal of Psychopharmacology·Kirsten A Oinonen, Roxanne Sterniczuk

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