Genetic locus, distant from ptsM, affecting enzyme IIA/IIB function in Escherichia coli K-12.

Journal of Bacteriology
R A Roehl, R T Vinopal

Abstract

Most strains of Escherichia coli K-12 are unable to use the enzyme IIA/IIB (enzyme IIMan) complex of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) in anaerobic growth and therefore cannot utilize glucosamine anaerobically. Introduction into these strains of a ptsG mutation, which eliminates activity of the enzyme IIIGlc/IIB' complex of the PTS, resulted in inability to grow anaerobically on glucose and mannose. Derivative strains able to grow anaerobically on glucosamine had mutations at a locus close to man, the gene coding for phosphomannose isomerase, and had higher enzyme IIA/IIB activities during anaerobic growth than did the parental strain. These results establish a locus affecting function of enzyme IIA/IIB that maps distant from ptsM, the probable structural gene for enzyme IIB.

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Citations

Aug 28, 1999·The Journal of Biological Chemistry·S Y KimS Ryu
Nov 3, 2005·The Journal of Biological Chemistry·Katja BettenbrockErnst-Dieter Gilles
Dec 13, 2006·Microbiology and Molecular Biology Reviews : MMBR·Josef DeutscherPieter W Postma
Aug 28, 2012·Journal of Bacteriology·Sonja Steinsiek, Katja Bettenbrock
Jul 28, 2020·Biochimica Et Biophysica Acta. Biomembranes·Jean-Marc Jeckelmann, Bernhard Erni
Apr 28, 1988·Biochimica Et Biophysica Acta·S A WoodsJ R Guest
Sep 1, 1985·Microbiological Reviews·P W Postma, J W Lengeler
Aug 1, 1985·Journal of Bacteriology·P W MorrisP L Kuempel
Sep 8, 1998·Microbiology and Molecular Biology Reviews : MMBR·M K Berlyn
Sep 1, 1993·Microbiological Reviews·P W PostmaG R Jacobson
Dec 1, 1993·Microbiological Reviews·M Riley
Feb 1, 1988·Journal of Bacteriology·T M HillP L Kuempel

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