PMID: 9532734Apr 9, 1998Paper

Genetic organization and function of the aflatoxin B1 biosynthetic genes

FEMS Microbiology Letters
C P Woloshuk, R Prieto

Abstract

Aflatoxins are secondary metabolites produced by Aspergillus flavus and Aspergillus parasiticus. Most of the genes involved in the biosynthesis of aflatoxin are contained within a single cluster in the genome of these filamentous fungi. Studies directed toward understanding the molecular biology of aflatoxin biosynthesis have led to a number of important discoveries. A pair of fatty acid synthase genes were identified that are involved uniquely in aflatoxin biosynthesis. Two genes were also characterized that represent new families of cytochrome P450 monooxygenases. Gene expression is coordinated during aflatoxin production and is under the control of a positive regulatory gene belonging to a family of fungal transcriptional activators associated with various metabolic pathways in fungi.

References

May 1, 1987·Applied and Environmental Microbiology·D BhatnagarR A Hill
Aug 1, 1995·Applied and Environmental Microbiology·C P WoloshukG A Payne
Apr 1, 1995·Microbiology·F TrailJ Linz
Mar 1, 1995·Proceedings of the Society for Experimental Biology and Medicine·T E MasseyL Liu
May 1, 1994·Applied and Environmental Microbiology·N P KellerT H Adams
Jan 1, 1994·Annual Review of Pharmacology and Toxicology·D L Eaton, E P Gallagher
Jul 1, 1994·Applied and Environmental Microbiology·C P WoloshukG A Payne
Jan 1, 1993·Applied and Environmental Microbiology·G A PayneC P Woloshuk
May 1, 1993·Applied and Environmental Microbiology·C D SkoryJ E Linz
Feb 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·D W BrownT J Leonard
Nov 1, 1996·Applied and Environmental Microbiology·H S KelkarT H Adams
Dec 10, 1996·Proceedings of the National Academy of Sciences of the United States of America·D W BrownN P Keller
Feb 1, 1997·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·S K Roy, A P Kulkarni

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Citations

Mar 26, 2003·Applied Microbiology and Biotechnology·D BhatnagarT E Cleveland
Jan 5, 2000·Applied and Environmental Microbiology·N P KellerC A Townsend
Feb 7, 2003·Applied and Environmental Microbiology·Zsuzsanna MayerRolf Geisen
Jan 5, 2002·Applied and Environmental Microbiology·Ching-Hsun ChiouJohn E Linz
Sep 9, 2004·Microbiology and Molecular Biology Reviews : MMBR·Eckhart Schweizer, Jörg Hofmann
Jun 4, 2005·Applied and Environmental Microbiology·Emi SakunoHiromitsu Nakajima
Jan 24, 2016·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Nidhal ZouaouiMaria-Jose Ruiz
Feb 26, 2016·Applied Microbiology and Biotechnology·Mauricio S AntunesNicholas C Carpita
Oct 9, 2008·Biotechnology Advances·David Lubertozzi, Jay D Keasling
May 20, 2008·Fungal Genetics and Biology : FG & B·Jingjing CaiKimiko Yabe
Mar 29, 2007·Natural Product Reports·Dirk Hoffmeister, Nancy P Keller
Mar 12, 2004·Annual Review of Phytopathology·G A Payne, M P Brown
Aug 25, 2010·Quarterly Reviews of Biophysics·Timm MaierNenad Ban
Mar 4, 2020·Toxins·Isaura CaceresJean-Denis Bailly
Jul 1, 1999·FEMS Microbiology Letters·M J Sweeney, A D Dobson
Apr 16, 2008·Biological Reviews of the Cambridge Philosophical Society·Florian Pankewitz, Monika Hilker
Jun 10, 2010·Foodborne Pathogens and Disease·Rukaia M GashgariYoussuf A Gherbawy
Mar 11, 2017·Nature Communications·Jan GajewskiMartin Grininger
Mar 26, 2019·Chembiochem : a European Journal of Chemical Biology·Christina S HeilMartin Grininger
May 28, 2019·FEMS Microbiology Letters·Rooholla GhanbariEbrahim Molaee Aghaee
Dec 31, 2005·Microbiology·Chao-Zong LeeGwo-Fang Yuan
Sep 15, 2006·Preparative Biochemistry & Biotechnology·Robert M GenganMichael F Dutton
Jun 19, 2013·Critical Reviews in Food Science and Nutrition·Muhammad AbrarKhalid Waqas
Feb 9, 2021·Frontiers in Microbiology·Nancy NleyaMulunda Mwanza
Jan 8, 2013·Journal of Molecular Biology·Daniel BoehringerMarc Leibundgut
May 18, 1999·Fungal Genetics and Biology : FG & B·M P BrownG A Payne
Sep 9, 2000·Biochimica Et Biophysica Acta·J YuT E Cleveland
Feb 28, 2002·Fungal Genetics and Biology : FG & B·Joong-Hoon AhnJonathan D Walton
Oct 6, 1998·Applied and Environmental Microbiology·D M MeyersG A Payne
Feb 15, 2008·Mycological Research·Ellen M Fox, Barbara J Howlett
Mar 4, 2006·Science·Simon JenniNenad Ban

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