Genetic parameters and mapping quantitative trait loci associated with tibia traits in broilers

Genetics and Molecular Research : GMR
B N N RagognettiD P Munari

Abstract

Selection among broilers for performance traits is resulting in locomotion problems and bone disorders, once skeletal structure is not strong enough to support body weight in broilers with high growth rates. In this study, genetic parameters were estimated for body weight at 42 days of age (BW42), and tibia traits (length, width, and weight) in a population of broiler chickens. Quantitative trait loci (QTL) were identified for tibia traits to expand our knowledge of the genetic architecture of the broiler population. Genetic correlations ranged from 0.56 ± 0.18 (between tibia length and BW42) to 0.89 ± 0.06 (between tibia width and weight), suggesting that these traits are either controlled by pleiotropic genes or by genes that are in linkage disequilibrium. For QTL mapping, the genome was scanned with 127 microsatellites, representing a coverage of 2630 cM. Eight QTL were mapped on Gallus gallus chromosomes (GGA): GGA1, GGA4, GGA6, GGA13, and GGA24. The QTL regions for tibia length and weight were mapped on GGA1, between LEI0079 and MCW145 markers. The gene DACH1 is located in this region; this gene acts to form the apical ectodermal ridge, responsible for limb development. Body weight at 42 days of age was included in the mod...Continue Reading

Citations

Jan 8, 2019·Animal : an International Journal of Animal Bioscience·J C FaveriM C Ledur
Jul 18, 2019·Tropical Animal Health and Production·Dimas de Oliveira SantosHumberto Tonhati
Dec 4, 2019·Genome Génome / Conseil National De Recherches Canada·Jun GuoKe-Hua Wang

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