Jun 11, 2016

Genetic polymorphism of 8 Y-STR loci in native population of Isfahan province in central part of Iran

Annals of Human Biology
Nasimeh VatandoostRasoul Salehi

Abstract

Y-chromosome short tandem repeats (Y-STRs) are genetic markers with practical applications in human identification and population studies. Here we present the allelic and haplotype frequencies of 8 Y-STR loci most commonly used in forensic medicine in 103 unrelated native males of Isfahan province, central part of Iran. The cases were selected on the basis of strict criteria to assure pure native populations of Isfahan origin. DNA extracted from peripheral blood samples and PCR amplified for each marker. Y-specific STR loci DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393 were included in this study. The most common alleles for each locus were: DYS19, allele 12; DYS385, allele 12; DYS389I, allele 13; DYS389II, allele 29; DYS390, allele 24; DYS391, allele 10; DYS392, allele 11; and DYS393, allele 13. Gene diversity value was calculated from the allelic frequency for each locus. The average gene diversity was 0.6518. A total of 101 haplotypes were observed in eight Y-specific STR loci, the haplotype diversity was raised to 0.986. The results revealed that a set of eight Y-specific STR loci were able to discriminate most of the male individuals in the population studied. A search through the Y Haplotype Referenc...Continue Reading

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Mentioned in this Paper

Biological Markers
Gene Polymorphism
Study
Short Tandem Repeat
Tandem Repeat Sequences
Genes
Peripheral Blood
Indonesia Zebrafish
Chromosomes, Human, Y
Genetic Markers

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