Genetic study of 12 X-STRs in Malay population living in and around Kuala Lumpur using Investigator Argus X-12 kit.

International Journal of Legal Medicine
Michinaga SamejimaK Minaguchi

Abstract

We investigated 12 X-chromosomal short tandem repeat (STR) polymorphisms in 283 unrelated Malay individuals (160 males and 123 females) living in and around Kuala Lumpur using the Investigator Argus X-12 kit. Heterozygosity among the present 12 X-STRs showed a distribution of from 55.3 to 93.5 %. The diversity values of the haplotypes constructed using four closely linked groups were all higher than 0.9865. A comparison of allelic frequency in each system and haplotype variation indicated that the nature of these X-STRs in the Malay population differed from that in East Asian, European, or African populations. Several microvariant alleles found in the Malay population were characterized and compared with known sequence data. The present data may be helpful in forensic casework such as personal identification and kinship testing in the Malay population in Malaysia.

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Citations

Apr 12, 2014·Electrophoresis·Hao-Tian MengXing Wei
Dec 2, 2014·Forensic Science International. Genetics·Carla BiniSusi Pelotti
Aug 15, 2014·Forensic Science International. Genetics·Xiao-na LiBao-jie Wang
Apr 10, 2016·International Journal of Legal Medicine·Kornkiat VongpaisarnsinPiyawan Dangkao
May 3, 2015·Forensic Science International. Genetics·Toni M Diegoli
May 5, 2016·Journal of Zhejiang University. Science. B·Yu-Xin GuoBo-Feng Zhu
Jan 30, 2014·Molecular Biology Reports·Heloísa Afonso CostaAntónio Amorim
Mar 1, 2017·International Journal of Legal Medicine·Takeki NishiKimiharu Iwadate
Oct 23, 2020·International Journal of Legal Medicine·Carla BiniDonata Luiselli

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