Genetic susceptibility to thrombosis.

Current Atherosclerosis Reports
James P LuyendykNigel Mackman

Abstract

Thrombosis is associated with atherosclerosis, sepsis, cancer, and numerous other inflammatory diseases. Complications of thrombosis, such as myocardial infarction, stroke, and venous thromboembolism, contribute significantly to morbidity and mortality. Susceptibility to thrombosis is conferred by both genetic and environmental factors. Tissue factor is the primary cellular initiator of blood coagulation and is a major contributor to thrombosis. In this review, we discuss the association between various polymorphisms and the risk for thrombosis.

References

Sep 13, 1994·Proceedings of the National Academy of Sciences of the United States of America·A CeliB Furie
Jul 1, 1995·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·N Mackman
Mar 1, 1997·The Journal of Clinical Investigation·R C JohnsonD D Wagner
Jul 17, 1999·Atherosclerosis·E TremoliS Colli
Jun 3, 2000·Nature Genetics·N C ArbourD A Schwartz
Feb 13, 2001·Annual Review of Medicine·A E BeckerA C van Der Wal
Feb 13, 2001·European Journal of Clinical Investigation·C DongerF Cambien
Feb 22, 2001·Biochemical and Biophysical Research Communications·A ZillmannB Engelmann
Mar 21, 2001·Cellular Signalling·M Guha, N Mackman
Jul 19, 2001·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·D MoattiD de Prost
Aug 13, 2003·Journal of Thrombosis and Haemostasis : JTH·A M CarterP J Grant
Oct 18, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Nejma AmezianeDominique de Prost
Jan 7, 2004·Cellular Microbiology·Robert J BellandGerald I Byrne
Mar 17, 2004·Current Opinion in Lipidology·Barbara Voetsch, Joseph Loscalzo
May 1, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Nigel Mackman
Oct 2, 2004·American Heart Journal·Vanessa RoldánJavier Corral
Dec 4, 2004·Stroke; a Journal of Cerebral Circulation·Robert Y L ZeePaul M Ridker
Apr 23, 2005·Arteriosclerosis, Thrombosis, and Vascular Biology·Nadine BrodalaTimothy C Nichols
Aug 17, 2005·Journal of Thrombosis and Haemostasis : JTH·J PolgarD D Wagner
Nov 8, 2005·Thrombosis and Haemostasis·Matthias HokeSabine Eichinger
Dec 3, 2005·The Journal of Clinical Investigation·Bruce Furie, Barbara C Furie

❮ Previous
Next ❯

Citations

Apr 29, 2009·Thrombosis Research·Thomas A WhiteRobert D Simari
Jun 9, 2007·Experimental and Molecular Pathology·Lobna Bouaziz-BorgiTouhami Mahjoub
Jul 12, 2008·Acta Neurologica Scandinavica·W GrisoldW Struhal
Aug 29, 2007·Oncology Nursing Forum·Nancy Eisenson
Aug 26, 2015·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·S MoussaouiN Abadi
Dec 10, 2016·International Journal of Legal Medicine·Francesco BrandimartiAdriano Tagliabracci

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.