Abstract
Background: Recent advances in less-invasive surgery and electrode design allow for a high degree of hearing preservation (HP) after cochlear implantation (CI), although residual hearing still deteriorates in some patients. To date, the factors predictive of preserving residual hearing remain a controversial topic.Objective: The aim of this study was to investigate the predictive factors, including the etiology of hearing loss (HL) as a patient-related factor, influencing residual HP after CI.Methods: Forty-four patients (50 ears, 41 families) with residual acoustic hearing who underwent CI were included. Auditory thresholds before and at 6 months after initial activation were measured. Genetic testing was performed to identify the responsible genes for HL.Results: We identified the cause of HL in 21 families (51.2%). HP was marginally correlated with age at implantation, while it was independent of pre-operative low-frequency hearing thresholds, cochlear duct length, and electrode length. We found that patients who had pathogenic variants in the CDH23, MYO7A, or MYO15A gene showed statistically better HP scores compared with patients with HL due to other causes (p = .002).Conclusions: Identification of the etiology of HL using...Continue Reading
References
Jan 7, 2011·Acta Oto-laryngologica·Shin-Ichi UsamiClaude Jolly
May 27, 2011·Audiology & Neuro-otology·Christoph A von IlbergOliver F Adunka
Dec 18, 2013·Acta Oto-laryngologica. Supplementum·Henryk SkarzynskiG Mertens
May 20, 2014·Acta Oto-laryngologica·Shin-Ichi UsamiTetsuya Tono
Aug 15, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Craig A BuchmanHarold C Pillsbury
Dec 3, 2014·Hearing Research·Ingeborg HochmairClaude Jolly
Mar 20, 2015·The Annals of Otology, Rhinology, and Laryngology·Shin-Ya Nishio, Shin-Ichi Usami
Mar 31, 2015·The Annals of Otology, Rhinology, and Laryngology·Shin-Ya NishioShin-Ichi Usami
Jun 17, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Marie-Charlot SuhlingThomas Lenarz
Jun 24, 2017·The Laryngoscope·George B WannaDavid S Haynes
Nov 18, 2017·Acta Oto-laryngologica·Masahiro TakahashiShin-Ichi Usami
Jun 19, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Silke HelbigTobias Weissgerber
Oct 31, 2018·Seminars in Hearing·Christopher WelchHarold C Pillsbury
Feb 1, 2019·Acta Oto-laryngologica·Hideaki MotekiShin-Ichi Usami
Mar 29, 2019·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Henryk SkarzynskiPiotr H Skarzynski
Jul 19, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Piotr H SkarzynskiArtur Lorens
Feb 7, 2020·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shin-Ichi UsamiHidekane Yoshimura
Citations
Apr 6, 2021·Acta Oto-laryngologica·Anandhan Dhanasingh, Ingeborg Hochmair
Jun 23, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kristen L SeligmanRichard J H Smith
Jun 26, 2021·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Leslie P Molina-RamírezGraeme C Black