PMID: 11344043May 10, 2001Paper

Genetic toxicology of a paradoxical human carcinogen, arsenic: a review

Mutation Research
Anamika BasuAshok K Giri

Abstract

Arsenic is widely distributed in nature in air, water and soil in the form of either metalloids or chemical compounds. It is used commercially, as pesticide, wood preservative, in the manufacture of glass, paper and semiconductors. Epidemiological and clinical studies indicate that arsenic is a paradoxical human carcinogen that does not easily induce cancer in animal models. It is one of the toxic compounds known in the environment. Intermittent incidents of arsenic contamination in ground water have been reported from several parts of the world. Arsenic containing drinking water has been associated with a variety of skin and internal organ cancers. The wide human exposure to this compound through drinking water throughout the world causes great concern for human health. In the present review, we have attempted to evaluate and update the mutagenic and genotoxic effects of arsenic and its compounds based on available literature.

References

Aug 1, 1977·Environmental Health Perspectives·T G RossmanW Troll
Jan 1, 1977·Advances in Experimental Medicine and Biology·C P Flessel
Apr 17, 1979·Human Genetics·I NordensonG Beckman
Jun 1, 1975·Mutation Research·H Nishioka
Jan 1, 1976·Mutation Research·Y ShirasuT Kada
Aug 1, 1977·Environmental Health Perspectives·G BeckmanI Nordenson
Aug 1, 1977·Environmental Health Perspectives·J PetresM Hagedorn
Dec 16, 1992·Mutation Research·A N JhaA T Natarajan
Jan 1, 1992·Environmental and Molecular Mutagenesis·J K Wiencke, J W Yager
Jan 1, 1992·Bulletin of Environmental Contamination and Toxicology·G EndoS Horiguchi
Jan 1, 1992·Pharmacology & Therapeutics·E T Snow
Jul 1, 1989·Biological Trace Element Research·J H Li, T G Rossman
Jul 1, 1989·Biological Trace Element Research·J C BarrettT C Lee
Nov 30, 1989·Biochemical and Biophysical Research Communications·K YamanakaS Okada
Oct 1, 1989·Chemical & Pharmaceutical Bulletin·K YamanakaS Okada
Jan 1, 1988·Mutation Research·M D Shelby
Jul 1, 1988·Science·T C LeeJ C Barrett
Sep 20, 1986·Journal of Molecular Biology·N Mitchell, G Stöhrer
Jan 1, 1986·Human Heredity·L Beckman, I Nordenson
Oct 1, 1986·Archives of Toxicology·W U MüllerC Fischer-Lahdo
Jul 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·W M JongenP Hagel
Apr 1, 1985·Journal of Applied Toxicology : JAT·L NagymajtényiG Berencsi
May 1, 1972·Journal of Agricultural and Food Chemistry·K J AndersonM T Takahashi

❮ Previous
Next ❯

Citations

Mar 23, 2010·International Archives of Occupational and Environmental Health·R A MateucaM Kirsch-Volders
Jan 19, 2006·Environmental Monitoring and Assessment·Ewa Terlecka
Dec 4, 2003·Mutation Research·Toby G Rossman
Oct 31, 2008·Talanta·S Garcia-ManyesG Rauret
Apr 8, 2003·Toxicology·Xing Hui ZhengA Jay Gandolfi
May 17, 2003·Toxicology Letters·Vanina BurnichonJean Louis Bergé-Lefranc
Nov 24, 2001·Mutation Research·Yasuhiro NodaShoji Okada
May 5, 2007·Journal of Toxicology and Environmental Health. Part a·Qi-Zhan LiuZhi-Xiong Zhuang
Mar 15, 2003·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·M Manzurul HassanChristine E Dunn
Mar 15, 2003·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·S J S FloraD K Jaiswal
Dec 19, 2002·Journal of the National Cancer Institute·William E AchanzarMichael P Waalkes
Mar 18, 2004·Journal of the National Cancer Institute·Michael P WaalkesBhalchandra A Diwan
Jul 21, 2010·Mutagenesis·Megan J OsmondElizabeth T Snow
Jun 16, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Adriana Sampayo-ReyesRicardo Marcos
Jul 14, 2011·Toxicological Sciences : an Official Journal of the Society of Toxicology·Michael F HughesDavid J Thomas
Mar 13, 2008·Pharmacogenetics and Genomics·Alba HernándezRicardo Marcos
Jan 24, 2003·Journal of Epidemiology and Community Health·P VineisM Manuguerra
Jul 31, 2013·BMC Complementary and Alternative Medicine·Manish K SinghSanjay Khattri
Apr 5, 2013·PloS One·Zhangqi ShenQijing Zhang
Apr 9, 2008·Journal of Clinical Biochemistry and Nutrition·Sutapa MukherjeeRathindra K Bhattacharya
Apr 16, 2013·International Journal of Environmental Research and Public Health·Francesca FaitaMaria Grazia Andreassi
Jan 6, 2010·International Journal of Environmental Research and Public Health·Dragan R MilićevićSrdan M Stefanović
Mar 10, 2015·The Science of the Total Environment·Yolanda Jasso-PinedaIvan Nelinho Pérez-Maldonado
Dec 24, 2013·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·Alba HernándezRicard Marcos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.