PMID: 7013620Jan 1, 1980Paper

Genetic variation among hepatitis B and related viruses

Annals of the New York Academy of Sciences
W S Robinson

Abstract

Hepatitis B virus (HBV) of man has several characteristics that distinguish it from viruses of other groups. These include its ultrastructure, viral DNA size and structure, a virion DNA polymerase which repairs a single-stranded region in the viral DNA, liver tropism, character of persistent infection, and association with hepatitis and hepatocellular carcinoma. Recently three other viruses have been found in other animal species that appear to share these characteristics although the viruses are not identical. HBV, Woodchuck hepatitis virus (WHV), ground squirrel hepatitis virus (GSHV), and duck hepatitis virus (DHV) appear to be members of a new virus group that might be designated the Hepadna virus group. Genetic variation among hepatitis B viruses includes the antigenic variation in the surface antigen (HBsAg) which constitutes the known HBsAg subtypes. There is also frequent variation in DNA base sequence among HBVs isolated from different patients.

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Citations

Jan 1, 1986·Medical Microbiology and Immunology·O Spertini, P C Frei
Jan 1, 1987·Pharmacology & Therapeutics·W S RobinsonP L Marion
Oct 11, 2002·Proceedings of the National Academy of Sciences of the United States of America·Priscilla L YangFrancis V Chisari
May 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·E Schaeffer, J J Sninsky
Nov 1, 1992·Journal of Gastroenterology and Hepatology·W S Robinson
Sep 19, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Dimitrios ParaskevisAngelos Hatzakis
Jan 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·W S RobinsonP L Marion
May 1, 1985·Journal of Medical Virology·T F McCaulA J Zuckerman
Jan 1, 1983·Journal of Medical Virology·H A FieldsD W Bradley
Jul 1, 1988·The Korean Journal of Internal Medicine·B C YooJ S Seo
Jul 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K N TsiquayeA J Zuckerman
Nov 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M UnouraH Yoshikawa
Jan 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S OhnishiS Kaneko
Sep 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H LeeT Kitagawa
Jul 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T UchidaT Shikata
Jan 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T UchidaT Shikata
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